SDR9C7

Description		short chain dehydrogenase/reductase family 9C member 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	All-trans-retinol Dehydrogenase (NAD+) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Steroid Metabolic Process Retinol Metabolic Process
Pathways		The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases
GWAS		Alzheimer's disease (survival time) ( 25649651) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Cerebral amyloid deposition (PET imaging) ( 30361487) Depressive symptoms (binary sum-score) ( 31530331) Familial lung cancer ( 29924316) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: INHBE
Interacting Genes		1 interacting genes: CFTR
Entrez ID		121214
HPRD ID		15235
Ensembl ID		ENSG00000170426
Uniprot IDs		Q8NEX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Negative Regulation Of Adipose Tissue Development Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Regulation Of Adipose Tissue Development Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Activin Receptor Signaling Pathway Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH
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