SEH1L and ATP6V0A1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SEH1L	ATP6V0A1
Gene Name		SEH1-like (S. cerevisiae)	ATPase, H+ transporting, lysosomal V0 subunit a1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Cytosol Nuclear Pore Outer Ring	Vacuolar Proton-transporting V-type ATPase, V0 Domain Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function		Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Mitotic Cell Cycle Cytokine Production Involved In Inflammatory Response Carbohydrate Metabolic Process Nuclear Pore Organization Mitotic Nuclear Envelope Disassembly Mitotic Metaphase Plate Congression Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Defense Response To Gram-positive Bacterium MRNA Transport Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Transmembrane Transport	Cellular Iron Ion Homeostasis Vacuolar Acidification Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Vacuolar Proton-transporting V-type ATPase Complex Assembly Phagosome Maturation
Pathways			Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: ATP6V0A1	4 interactors: CLIC1 SEH1L SNX4 ZNF267
Entrez ID		81929	535
HPRD ID		15319	01886
Ensembl ID		ENSG00000085415	ENSG00000033627
Uniprot IDs		Q96EE3	B7Z2A9 B7Z641 Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs
Enriched GO Terms of Interacting Partners?		Vacuolar Proton-transporting V-type ATPase Complex Assembly Vacuolar Acidification Intracellular PH Reduction PH Reduction Transferrin Transport ATP Synthesis Coupled Proton Transport ATP Biosynthetic Process Phagosome Maturation Regulation Of Intracellular PH Regulation Of Cellular PH ATP Hydrolysis Coupled Proton Transport Regulation Of PH Purine Ribonucleoside Monophosphate Biosynthetic Process Iron Ion Transport Cellular Iron Ion Homeostasis Nucleoside Triphosphate Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Interaction With Host Nucleoside Monophosphate Biosynthetic Process Iron Ion Homeostasis ATP Metabolic Process Transition Metal Ion Homeostasis Insulin Receptor Signaling Pathway Purine Nucleotide Biosynthetic Process Hydrogen Ion Transmembrane Transport Ribose Phosphate Biosynthetic Process Cellular Response To Insulin Stimulus Proton Transport Purine Nucleoside Metabolic Process Response To Insulin Ribonucleotide Metabolic Process Nucleoside Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Cellular Response To Peptide Hormone Stimulus Ribose Phosphate Metabolic Process Cellular Response To Peptide Cellular Protein Complex Assembly Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Response To Peptide Hormone Cellular Response To Organonitrogen Compound Metal Ion Homeostasis Response To Peptide Cellular Chemical Homeostasis Ion Homeostasis Nucleotide Metabolic Process Cellular Response To Hormone Stimulus Cellular Macromolecular Complex Assembly	Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Attachment Of Mitotic Spindle Microtubules To Kinetochore Cytokine Production Involved In Inflammatory Response Nuclear Pore Organization Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mast Cell Degranulation Positive Regulation Of Mast Cell Activation Positive Regulation Of Regulated Secretory Pathway Endocytic Recycling Regulation Of Ion Transport Regulation Of Mast Cell Degranulation Production Of Molecular Mediator Involved In Inflammatory Response Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Mitochondrial Membrane Potential Mitotic Nuclear Envelope Disassembly Regulation Of Mast Cell Activation Platelet Aggregation Regulation Of Regulated Secretory Pathway Nuclear Envelope Disassembly Establishment Of Chromosome Localization
Tagcloud ?			acidification atpase autophagosomes betaa1 betaa3 cko coimmunoprecipitates cryba1 crystallin ctsd droplets electroretinography endolysosomal fundus helping knocked phagocytic phagocytosis photographs photoreceptor pigment pmtor raptor rpe rptor scattered undigested vacuole
Tagcloud (Difference) ?			acidification atpase autophagosomes betaa1 betaa3 cko coimmunoprecipitates cryba1 crystallin ctsd droplets electroretinography endolysosomal fundus helping knocked phagocytic phagocytosis photographs photoreceptor pigment pmtor raptor rpe rptor scattered undigested vacuole
Tagcloud (Intersection) ?