SGPP1 and S1PR5

Number of citations of the paper that reports this interaction (PMID 11069896)
15

Data Source:
BioGRID (pull down)

		SGPP1	S1PR5
Gene Name		sphingosine-1-phosphate phosphatase 1	sphingosine-1-phosphate receptor 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Sphingosine-1-phosphate Phosphatase Activity	Sphingosine-1-phosphate Receptor Activity
	Biological Process	Sphingolipid Metabolic Process Sphinganine-1-phosphate Metabolic Process Sphingosine Metabolic Process Dephosphorylation Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Extrinsic Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway	Sphingosine-1-phosphate Signaling Pathway Regulation Of Neuron Differentiation
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Sphingolipid levels ( 19798445 22359512)
Protein-Protein Interactions		1 interactors: S1PR5	4 interactors: GNA12 GNAI1 GNAO1 SGPP1
Entrez ID		81537	53637
HPRD ID		10226	05510
Ensembl ID		ENSG00000126821	ENSG00000180739
Uniprot IDs		Q9BX95	Q9H228
PDB IDs
Enriched GO Terms of Interacting Partners?		Sphingosine-1-phosphate Signaling Pathway	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Surface Receptor Signaling Pathway Sphinganine-1-phosphate Metabolic Process Platelet Activation G-protein Coupled Receptor Signaling Pathway Blood Coagulation Hemostasis Sphingosine Metabolic Process Signal Transduction Response To Drug Signaling Regulation Of Body Fluid Levels Cell Communication Wound Healing Cell Activation Response To Wounding Regulation Of Fibroblast Migration Dopamine Receptor Signaling Pathway Cellular Response To Stimulus Response To Morphine Negative Regulation Of Calcium Ion Transport Response To Organonitrogen Compound Vesicle Fusion Rho Protein Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of TOR Signaling
Tagcloud ?			aqpep bcl2l11 clic6 dock1 en1 ephx3 fbxo17 fndc1 foxe1 foxl1 gbx2 gstm5 insrr irx3 lbx2 loxl1 meis1 mt1h nr2f2 parvg phkg1 pitx1 pnliprp1 pou3f3 rasal slc35d3 tbx4 tfap2c xrn2
Tagcloud (Difference) ?			aqpep bcl2l11 clic6 dock1 en1 ephx3 fbxo17 fndc1 foxe1 foxl1 gbx2 gstm5 insrr irx3 lbx2 loxl1 meis1 mt1h nr2f2 parvg phkg1 pitx1 pnliprp1 pou3f3 rasal slc35d3 tbx4 tfap2c xrn2
Tagcloud (Intersection) ?