TSEN2 and RANBP10

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		TSEN2	RANBP10
Gene Name		TSEN2 tRNA splicing endonuclease subunit	RAN binding protein 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus Cytoplasm Centrosome	Nucleus Cytosol Cytoplasmic Microtubule
	Molecular Function	TRNA-intron Endonuclease Activity Nucleic Acid Binding Lyase Activity	Ran Guanyl-nucleotide Exchange Factor Activity Ran GTPase Binding Beta-tubulin Binding
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing RNA Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Microtubule Cytoskeleton Organization Positive Regulation Of Ran GTPase Activity
Pathways
Drugs
Diseases
GWAS		Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		2 interactors: RANBP10 TSEN54	11 interactors: CACHD1 CNTNAP4 IGSF1 MEGF10 MET NEDD4 NEDD4L PRKCG RAN THSD7B TSEN2
Entrez ID		80746	57610
HPRD ID		10576	15207
Ensembl ID		ENSG00000154743	ENSG00000141084
Uniprot IDs		Q8NCE0	B4DQH9 Q6VN20 R4GMX8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ran GTPase Activity TRNA Splicing, Via Endonucleolytic Cleavage And Ligation	Negative Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Regulation Of Potassium Ion Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Sodium Ion Transport Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Positive Regulation Of Mismatch Repair Skeletal Muscle Satellite Cell Proliferation Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Protein Catabolic Process Negative Regulation Of Ion Transport Regulation Of Mismatch Repair Skeletal Muscle Cell Proliferation Skeletal Muscle Satellite Cell Activation Positive Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Cellular Response To Growth Factor Stimulus Ribosomal Small Subunit Export From Nucleus Viral Process Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Skeletal Muscle Organ Development TRNA-type Intron Splice Site Recognition And Cleavage Protein Polyubiquitination Cell Activation Progesterone Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Myoblast Proliferation Regulation Of Caveolin-mediated Endocytosis Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Skeletal Muscle Satellite Cell Differentiation Negative Regulation Of Sodium Ion Transmembrane Transport Viral Life Cycle Positive Regulation Of Transport Intracellular Receptor Signaling Pathway Ribosomal Large Subunit Export From Nucleus Hepatocyte Growth Factor Receptor Signaling Pathway Recognition Of Apoptotic Cell Regulation Of Grooming Behavior Protein Autophosphorylation Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
Tagcloud ?			actr1a backgrounds bbs2 bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia rps15a rps9 slc30a6 suitability suz12 uxt znf131
Tagcloud (Difference) ?			actr1a backgrounds bbs2 bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia rps15a rps9 slc30a6 suitability suz12 uxt znf131
Tagcloud (Intersection) ?