ULBP2 and YIPF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ULBP2	YIPF6
Description		UL16 binding protein 2	Yip1 domain family member 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Side Of Membrane	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Golgi Medial Cisterna Cis-Golgi Network Trans-Golgi Network Endomembrane System Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Protein Binding GPI Anchor Binding Natural Killer Cell Lectin-like Receptor Binding Receptor Ligand Activity	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Immune System Process Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Signal Transduction Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intestinal Epithelial Cell Development
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Neurological blood protein biomarker levels ( 31320639)	Male-pattern baldness ( 28196072)
Interacting Genes		3 interacting genes: DERL3 PDGFRA YIPF6	93 interacting genes: APOL2 AQP2 AQP6 ARL13B ATP6V0E1 CD79A CGRRF1 CISD2 CLN8 CNR2 CPLX4 CRB3 CREB3L1 CREB3L3 CXorf66 CYSLTR2 EBP EFNA5 ELOVL4 ERGIC3 F2RL1 FAM209A FCER1G FFAR2 FKBP7 GJA5 GJA8 GJB1 GPR101 GPR152 GPR42 GPX8 HSD17B11 IL10RA IL1RL1 IL27RA JKAMP KCNJ6 KCNK5 LMNA LRRC25 LRRC3B LRRC4C LY6G6C LYVE1 MMD MS4A3 MTIF3 MUC1 NDUFAF1 ODF4 PDZK1IP1 PSCA RAET1L REEP4 RETREG3 RHCG RNF185 SCN3B SLC10A1 SLC10A6 SLC12A7 SLC17A8 SLC18A1 SLC30A4 SLC30A8 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SLC61A1 SLC71A2 SLC7A14 SLC7A8 SSMEM1 STOM TCTA THAP4 TMEM106C TMEM11 TMEM130 TMEM14B TMEM237 TMEM31 TMEM52B TMEM71 TMX2 TRARG1 TRHR TVP23B ULBP2 YIPF1 YIPF2
Entrez ID		80328	286451
HPRD ID		16143	06639
Ensembl ID		ENSG00000131015	ENSG00000181704
Uniprot IDs		Q9BZM5	Q96EC8
PDB IDs		8IMX 8IMY
Enriched GO Terms of Interacting Partners?		Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Platelet-derived Growth Factor Alpha-receptor Activity Phospholipase C Activator Activity Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Metanephric Glomerular Capillary Formation Platelet-derived Growth Factor Receptor-ligand Complex Nuclear Matrix Anchoring At Nuclear Membrane Vascular Endothelial Growth Factor Binding Nuclear Matrix Organization Glomerular Capillary Formation Luteinization Protein-containing Complex Binding Vascular Endothelial Growth Factor Receptor Activity Platelet-derived Growth Factor Binding Leydig Cell Differentiation Golgi Apparatus Regulation Of Mesenchymal Stem Cell Differentiation Meiotic Nuclear Membrane Microtubule Tethering Complex Cytoskeleton-nuclear Membrane Anchor Activity Signal Recognition Particle Binding Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Protein Exit From Endoplasmic Reticulum Golgi Trans Cisterna Intestinal Epithelial Cell Development Golgi Medial Cisterna Regulation Of Retrograde Protein Transport, ER To Cytosol Platelet-derived Growth Factor Receptor Binding Retina Vasculature Development In Camera-type Eye Cardiac Myofibril Assembly Columnar/cuboidal Epithelial Cell Development Male Genitalia Development Lamin Binding Embryonic Digestive Tract Morphogenesis White Fat Cell Differentiation Negative Regulation Of Platelet Activation Vascular Endothelial Growth Factor Signaling Pathway Protein N-linked Glycosylation Via Asparagine Regulation Of Protein Exit From Endoplasmic Reticulum Reproductive System Development Adrenal Gland Development Female Gonad Development Maintenance Of Protein Location In Nucleus	Membrane Transmembrane Transport Plasma Membrane Protein Binding Endoplasmic Reticulum Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Monoatomic Cation Transport Zinc Ion Transmembrane Transport Zinc Ion Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Inorganic Ion Transmembrane Transport Regulation Of Renin Secretion Into Blood Stream Amino Acid Transmembrane Transport Connexin Complex Import Across Plasma Membrane Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Positive Regulation Of Acute Inflammatory Response Gap Junction Transmembrane Transporter Activity SA Node Cell Action Potential Side Of Membrane Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport Organic Anion Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Monoatomic Cation Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Renal Water Transport Monoatomic Ion Transmembrane Transport Gap Junction Assembly Golgi Trans Cisterna Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Ammonium Channel Activity G Protein-coupled Receptor Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Golgi Medial Cisterna
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