SP6 and MALSU1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SP6	MALSU1
Description		Sp6 transcription factor	mitochondrial assembly of ribosomal large subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytosol	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Ribosomal Large Subunit Binding Mitochondrial Large Ribosomal Subunit Binding
	Biological Process	Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II Odontogenesis Regulation Of Odontogenesis	Negative Regulation Of Translation Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Negative Regulation Of Mitochondrial Translation Negative Regulation Of Ribosome Biogenesis
Pathways			Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Asthma ( 31619474) Birth weight ( 27680694) Blond vs. brown/black hair color ( 30531825) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Hair color ( 29662168) Prostate cancer ( 34012061)
Interacting Genes		1 interacting genes: MALSU1	13 interacting genes: CHMP2B DCTD INCA1 LMO3 MEOX2 MYBPHL NTAQ1 PLEKHG4 SP6 TRIM55 TRIM63 ZFP90 ZNF426
Entrez ID		80320	115416
HPRD ID		12269	12918
Ensembl ID		ENSG00000189120	ENSG00000156928
Uniprot IDs		B3KXP2 Q3SY56	Q96EH3
PDB IDs			5OOL 5OOM 7A5H 7A5J 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF5 7OF7 7OI6 7OI7 7OI8 7OI9 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 8K2B 8PK0 8QSJ 8QU5
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Mitochondrial Translation Mitochondrial Large Ribosomal Subunit Binding Negative Regulation Of Ribosome Biogenesis Regulation Of Ribosome Biogenesis Ribosomal Large Subunit Binding Regulation Of Mitochondrial Translation Ribosomal Large Subunit Biogenesis Ribosome Biogenesis Negative Regulation Of Translation Ribonucleoprotein Complex Biogenesis
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