ITPKC and PPP3CC

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ITPKC	PPP3CC
Gene Name		inositol-trisphosphate 3-kinase C	protein phosphatase 3, catalytic subunit, gamma isozyme
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity	Phosphoprotein Phosphatase Activity Calmodulin Binding Metal Ion Binding
	Biological Process	Phosphorylation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process	Apoptotic Process Dephosphorylation Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways		Synthesis of IP3 and IP4 in the cytosol Inositol phosphate metabolism	Activation of BAD and translocation to mitochondria Signaling by GPCR Opioid Signalling Programmed Cell Death DARPP-32 events Activation of BH3-only proteins Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS		Kawasaki disease ( 22081228)	HIV-1 control ( 20205591)
Protein-Protein Interactions		1 interactors: PPP3CC	11 interactors: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B HAX1 ITPKC SDC2 TGFBR1 THAP7
Entrez ID		80271	5533
HPRD ID		09400	00236
Ensembl ID		ENSG00000086544	ENSG00000120910
Uniprot IDs		Q96DU7	P48454
PDB IDs		2A98
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport	Cell Morphogenesis Involved In Differentiation Axonogenesis Cell Morphogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Differentiation Regulation Of Binding Neuron Projection Morphogenesis Neuron Projection Development Cell Projection Morphogenesis Axon Guidance Cell Part Morphogenesis Generation Of Neurons Regulation Of Cell Differentiation Regulation Of Protein Binding Neurogenesis Neuron Development Cell Development Regulation Of Protein Phosphorylation Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Projection Organization Chemotaxis Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Protein Metabolic Process Cell Surface Receptor Signaling Pathway Gonad Development Locomotion Positive Regulation Of Signal Transduction Development Of Primary Sexual Characteristics Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Phosphorylation Negative Regulation Of Cell Proliferation Protein Phosphorylation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Response To Wounding Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Phosphorylation Nervous System Development Developmental Growth Sex Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Neuron Apoptotic Process Thymus Development Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Sexual Reproduction
Tagcloud ?			ankk1 ankyrin catechol comt contradicting disabilities drd2 economical google htt industrialized isozyme keywords kibra lifelong nefh neurofilament neurotrophic nos3 penetrating repercussions researches return roughly scholar slc6a4 solute tbi traumatic
Tagcloud (Difference) ?			ankk1 ankyrin catechol comt contradicting disabilities drd2 economical google htt industrialized isozyme keywords kibra lifelong nefh neurofilament neurotrophic nos3 penetrating repercussions researches return roughly scholar slc6a4 solute tbi traumatic
Tagcloud (Intersection) ?