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BCAS3
Description
BCAS3 microtubule associated cell migration factor
Image
No pdb structure
GO Annotations
Cellular Component
Phagophore Assembly Site
Euchromatin
Nucleus
Cytoplasm
Cytoskeleton
Cytoplasmic Microtubule
Cell Leading Edge
Intermediate Filament Cytoskeleton
Molecular Function
Chromatin Binding
Protein Binding
Acetyltransferase Activator Activity
Nuclear Receptor Binding
Histone Acetyltransferase Binding
Phosphatidylinositol Binding
Histone Binding
Beta-tubulin Binding
Biological Process
Angiogenesis
Autophagy
Cell-cell Signaling
Positive Regulation Of Endothelial Cell Migration
Regulation Of Actin Cytoskeleton Organization
Response To Starvation
Positive Regulation Of Catalytic Activity
Response To Estrogen
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Estrogen Stimulus
Pathways
Drugs
Diseases
GWAS
Airway responsiveness in chronic obstructive pulmonary disease (
25514360
)
Alzheimer's disease (cognitive decline) (
23535033
)
Blood urea nitrogen levels (
31152163
29403010
)
Bone ultrasound measurement (broadband ultrasound attenuation) (
28472463
)
Calcium levels (
29403010
)
Chronic kidney disease (
20383146
31152163
)
Coronary artery disease (
33020668
29212778
26343387
32469254
)
Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) (
28714975
)
Creatinine levels (
29403010
)
Estimated glomerular filtration rate (
30604766
31451708
29779033
31152163
)
Estimated glomerular filtration rate in diabetes (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
FEV1 (
30804560
)
Glomerular filtration rate (
27588450
29403010
)
Glomerular filtration rate (creatinine) (
28452372
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
Gout (
25967671
32238385
)
Gout (combined type) (
32238385
)
Heel bone mineral density (
28869591
30598549
)
Height (
18391951
)
Hematocrit (
27863252
32888494
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
High light scatter reticulocyte count (
32888494
)
Immune reponse to smallpox (secreted IL-2) (
22610502
)
Intraocular pressure (
31959993
29785010
30054594
29617998
)
Lung function (FEV1/FVC) (
30804560
)
Macular thickness (
30535121
)
Medial orbital frontal cortex volume (
31530798
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Medication use (diuretics) (
31015401
)
Myocardial infarction (
33532862
26343387
)
Obesity-related traits (
23251661
)
Optic cup area (
28073927
25631615
31798171
)
Optic disc size (
31809533
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Pulse pressure (
30578418
)
Red blood cell count (
27863252
32888494
)
Red cell distribution width (
32888494
)
Refractive error (
32231278
)
Renal function-related traits (BUN) (
22797727
)
Renal function-related traits (eGRFcrea) (
22797727
)
Renal function-related traits (sCR) (
22797727
)
Serum creatinine levels (
29779033
)
Serum uric acid levels (
29403010
30993211
32514006
)
Systolic blood pressure (
30578418
30224653
)
Thyroid stimulating hormone levels (
32769997
30367059
)
Urate levels (
31985003
31578528
23263486
)
Urolithiasis (
30975718
)
Vertical cup-disc ratio (
20548946
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Vitamin C levels (
33203707
)
Waist circumference adjusted for body mass index (
34021172
)
Interacting Genes
23 interacting genes:
ATM
BAG4
CCND1
CDC23
CTBP1
CTBP2
DDB1
FBXW7
H3C1
KRAS
MTDH
PALB2
PELP1
PHB1
PLEKHF2
PTPN1
SMAD4
STK11
TGFB1
TP53
TSG101
XRCC3
ZDHHC17
Entrez ID
54828
HPRD ID
06313
Ensembl ID
ENSG00000141376
Uniprot IDs
Q05D99
Q9H6U6
PDB IDs
Enriched GO Terms of Interacting Partners
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Protein-containing Complex Binding
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Programmed Cell Death
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Apoptotic Process
Regulation Of Cell Population Proliferation
Regulation Of Cell Cycle
Regulation Of Signal Transduction
Regulation Of Cell Cycle Phase Transition
Response To Radiation
Cellular Response To Radiation
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Neuron Apoptotic Process
Macromolecule Metabolic Process
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Response To Ionizing Radiation
Viral Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
Transcription Repressor Complex
Regulation Of ERK1 And ERK2 Cascade
Response To UV
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Growth
Regulation Of Cell Cycle Process
Response To Light Stimulus
Positive Regulation Of Apoptotic Process
Negative Regulation Of Macromolecule Metabolic Process
DNA Damage Response
Positive Regulation Of Programmed Cell Death
Negative Regulation Of RNA Metabolic Process
Cellular Response To UV
Response To X-ray
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Transcription Corepressor Activity
Developmental Growth
Negative Regulation Of Apoptotic Process
Negative Regulation Of Growth
Regulation Of Cell Growth
Cellular Response To Light Stimulus
Tagcloud
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