DHX29 and CENPT

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DHX29	CENPT
Description		DExH-box helicase 29	centromere protein T
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Eukaryotic 43S Preinitiation Complex Cytosolic Small Ribosomal Subunit	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Translation Initiation Factor Activity Helicase Activity ATP Binding Translation Activator Activity Hydrolase Activity Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Ribosomal Small Subunit Binding Cadherin Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Formation Of Translation Preinitiation Complex Translation Translational Initiation Ribosome Assembly Positive Regulation Of Translation Positive Regulation Of Translational Initiation	Mitotic Cell Cycle Chromosome Segregation Chromosome Organization Cell Division Kinetochore Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		3 interacting genes: CENPT PISD TBC1D17	8 interacting genes: APP CENPS COPS5 DHX29 H3C1 PPCDC SNCB TCEA2
Entrez ID		54505	80152
HPRD ID		10882	07811
Ensembl ID		ENSG00000067248	ENSG00000102901
Uniprot IDs		Q7Z478	B3KPB2 Q96BT3
PDB IDs			7QOO 7R5S 7XHN 7XHO 7YWX
Enriched GO Terms of Interacting Partners?		Phosphatidylserine Decarboxylase Activity Membraneless Organelle Assembly Phosphatidylethanolamine Biosynthetic Process Protein Autoprocessing Lipid Droplet Formation Mitochondrial Protein Catabolic Process Carboxy-lyase Activity Kinetochore Organization Kinetochore Assembly Inner Kinetochore Phosphatidylethanolamine Metabolic Process Organelle Assembly	Transition Metal Ion Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Translation Initiation Factor Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Protein Heterodimerization Activity Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Macrophage Migration Inhibitory Factor Binding Translational Initiation Nitric-oxide Synthase Complex
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