ZNF696 and CDC14B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF696	CDC14B
Description		zinc finger protein 696	cell division cycle 14B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cell Junction Mitotic Spindle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization DNA Repair Protein Dephosphorylation DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of Exit From Mitosis Positive Regulation Of Cytokinesis Cilium Assembly Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways		Generic Transcription Pathway	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Household income ( 31844048) Intelligence (MTAG) ( 29326435) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		30 interacting genes: CALCOCO2 CCDC136 CCNDBP1 CDC14B CEP70 CYSRT1 DVL3 GOLGA6L9 KRTAP1-1 KRTAP1-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP4-12 KRTAP5-9 KRTAP9-2 MDFI MID2 MTUS2 PDE4DIP RNF4 STX1A TENM4 TRIM41 ZNF526	20 interacting genes: BCL10 BUB1 CCND1 CDKN2A CHEK1 DLC1 MCC MFAP1 MLH3 MSH2 MTDH PRKAB2 PSMB1 SIRT2 SKP2 SMAD4 SPANXN2 STK11 TP53 ZNF696
Entrez ID		79943	8555
HPRD ID		08595	04615
Ensembl ID		ENSG00000185730	ENSG00000081377
Uniprot IDs		Q9H7X3	A0A9L9PY50 O60729
PDB IDs			1OHC 1OHD 1OHE
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Cytosol	Nucleus Nucleoplasm Regulation Of Cell Cycle Phase Transition Replicative Senescence Mitotic DNA Integrity Checkpoint Signaling Regulation Of Apoptotic Process Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Mitotic DNA Damage Checkpoint Signaling Regulation Of Cell Cycle Apoptotic Signaling Pathway Positive Regulation Of Execution Phase Of Apoptosis Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Response To X-ray Negative Regulation Of Mitotic Cell Cycle DNA Damage Checkpoint Signaling Negative Regulation Of Cell Cycle Phase Transition NF-kappaB Binding Regulation Of Cell Population Proliferation Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Process Intracellular Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Post-translational Protein Modification Centromeric DNA Binding Response To Ionizing Radiation Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Response To UV Positive Regulation Of Programmed Cell Death Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Growth Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Catabolic Process Positive Regulation Of Protein Modification Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Mismatched DNA Binding Regulation Of Protein Ubiquitination P53 Binding Regulation Of Protein Modification Process MDM2/MDM4 Family Protein Binding General Transcription Initiation Factor Binding Centrosome Negative Regulation Of Growth Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cellular Component Organization Mitotic G1 DNA Damage Checkpoint Signaling Mammary Gland Epithelial Cell Proliferation
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