ASB13 and HAPLN2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ASB13	HAPLN2
Name		ankyrin repeat and SOCS box containing 13	hyaluronan and proteoglycan link protein 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Extracellular Space Extracellular Matrix Node Of Ranvier Synapse Perineuronal Net
	Molecular Function	Protein Binding	Protein Binding Hyaluronic Acid Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction	Skeletal System Development Cell Adhesion Central Nervous System Development Establishment Of Blood-nerve Barrier Extracellular Matrix Assembly
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	None
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757 ) Fasting insulin ( 34074324 ) Leukocyte telomere length ( 32109421 ) Pulse pressure ( 30578418 )	No GWAS studies recorded
Interacting Genes		17 interacting genes: ASB9 DNM1 DUSP23 HAPLN2 HIF1AN KRTAP11-1 KRTAP15-1 MARK3 MSRB3 NUDT3 OXER1 POU6F2 TRIP13 UBAP2 VAC14 ZMIZ2 ZNF581	47 interacting genes: ASB13 BANP CCDC125 CIDEB EXOSC8 FHL3 FHL5 FNDC3B GOLGA6L9 GPRIN2 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT40 KRT85 KRTAP10-8 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP6-2 KRTAP6-3 KRTAP9-2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OIP5 PFDN5 PM20D2 PNMA1 PNMA2 PPP1R16B PSTPIP1 SEC13 SSC4D TFCP2 TRIM23 TRIM27 VWC2 ZMYND12 ZNF438 ZNF655
Entrez ID		79754	60484
HPRD ID		10667	17088
Ensembl ID		ENSG00000196372	ENSG00000132702
Uniprot IDs		Q8WXK3	B7Z1R1 Q9GZV7
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Vesicle Scission Clathrin Coat Assembly Involved In Endocytosis Meiotic Recombination Checkpoint Signaling 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity [protein]-asparagine 3-dioxygenase Activity Peptidyl-aspartic Acid 3-dioxygenase Activity Peptidyl-histidine Dioxygenase Activity PAS Complex Establishment Of Blood-nerve Barrier 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Identical Protein Binding Cytoskeleton Organization Epidermis Development Keratinization Negative Regulation Of Viral Transcription COPII Vesicle Coat Suppression Of Viral Release By Host Protein Binding COPII-coated Vesicle Cargo Loading Regulation Of Viral Transcription Cytosol Cytoskeleton