NOL9 and AHNAK

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NOL9	AHNAK
Description		nucleolar protein 9	AHNAK nucleoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Intermediate Filament Cytoskeleton	Nucleus Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane T-tubule Vesicle Sarcolemma Costamere Cell-cell Contact Zone Membrane Raft Extracellular Exosome Plasma Membrane Protein Complex
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding ATP Binding Kinase Activity Transferase Activity ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity	RNA Binding Protein Binding Identical Protein Binding S100 Protein Binding Cadherin Binding Structural Molecule Activity Conferring Elasticity
	Biological Process	Cleavage In ITS2 Between 5.8S RRNA And LSU-rRNA Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA RRNA Processing RNA Processing	Regulation Of RNA Splicing Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Plasma Membrane Repair
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Body mass index ( 25673413) Mean corpuscular hemoglobin concentration ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	A body shape index ( 34021172) Alanine aminotransferase levels ( 33547301) Alzheimer's disease (late onset) ( 28714976) Blond vs. brown/black hair color ( 30531825) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cutaneous melanoma or hair colour ( 32341527) Gamma glutamyl transferase levels ( 33339817 29403010) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591 30598549) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung function (FEV1) ( 28166213) Monocyte percentage of white cells ( 32888494) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Serum alkaline phosphatase levels ( 31666285) Triglyceride levels ( 32203549) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: AHNAK REL SUMO2 TCF4	13 interacting genes: AKT1 CDKN2A EGFR FNDC3B KLHL40 MEOX2 NOL9 POT1 S100B SUMO2 USP7 WEE2-AS1 XRCC4
Entrez ID		79707	79026
HPRD ID		08667	14684
Ensembl ID		ENSG00000162408	ENSG00000124942
Uniprot IDs		Q5SY16	B4DTV0 Q09666 Q9BVU3
PDB IDs			4DRW 4FTG 4HRG
Enriched GO Terms of Interacting Partners?		NF-kappaB Complex TFIIB-class Transcription Factor Binding Beta-catenin-TCF7L2 Complex Structural Molecule Activity Conferring Elasticity Positive Regulation Of Plasma Membrane Repair Negative Regulation Of Interferon-beta Production Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Protein Tag Activity Beta-catenin-TCF Complex Regulation Of Plasma Membrane Repair Costamere Regulation Of Plasma Membrane Organization Regulation Of Voltage-gated Calcium Channel Activity S100 Protein Binding Plasma Membrane Protein Complex Positive Regulation Of RNA Metabolic Process SUMO Transferase Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Ubiquitin-like Protein Ligase Binding Presynaptic Cytosol Postsynaptic Cytosol Cell-cell Contact Zone Non-canonical NF-kappaB Signal Transduction	Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Proteolysis Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Response To UV-A Negative Regulation Of Post-translational Protein Modification Negative Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator SUMO Transferase Activity Negative Regulation Of Protein Catabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Peptidyl-serine Phosphorylation Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Proteolysis Regulation Of DNA Metabolic Process Regulation Of Cellular Localization Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Myelination Regulation Of Cellular Response To Stress Regulation Of TRNA Methylation Response To Epidermal Growth Factor Ligase Inhibitor Activity Protein Sumoylation Multivesicular Body, Internal Vesicle Lumen FHA Domain Binding Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Catabolic Process Regulation Of Post-translational Protein Modification Nucleoplasm Positive Regulation Of Cell Cycle G1/S Phase Transition
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