SAP130 and SFT2D3

		SAP130	SFT2D3
Description		Sin3A associated protein 130	SFT2 domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck Sin3-type Complex	Cytoplasm Endomembrane System Membrane
	Molecular Function
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Protein Transport Vesicle-mediated Transport
Pathways		HATs acetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Coffee consumption ( 31046077) Coronary artery disease ( 29212778)
Interacting Genes		7 interacting genes: ARID4B CCR9 CUL2 GPS1 MYC SMAD3 USP7
Entrez ID		79595	84826
HPRD ID		18015	14683
Ensembl ID		ENSG00000136715	ENSG00000173349
Uniprot IDs		A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3	Q587I9
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromatin Remodeling Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Intracellular Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization MAPK Cascade Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Positive Regulation Of MiRNA Transcription JNK Cascade Positive Regulation Of MiRNA Metabolic Process Regulation Of Intracellular Transport Epigenetic Regulation Of Gene Expression Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin Protein Ligase Binding Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of MiRNA Transcription T Cell Activation Regulation Of Stem Cell Population Maintenance Myc-Max Complex Regulation Of Acinar Cell Proliferation Regulation Of Cellular Response To Growth Factor Stimulus Sterol Response Element Binding Regulation Of MiRNA Metabolic Process Paraxial Mesoderm Morphogenesis Cis-regulatory Region Sequence-specific DNA Binding Apoptotic Signaling Pathway NK T Cell Proliferation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Symbiont-mediated Disruption Of Host Cell PML Body CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance
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