SAP130 and NIFK

		SAP130	NIFK
Description		Sin3A associated protein 130	nucleolar protein interacting with the FHA domain of MKI67
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck Sin3-type Complex	Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm
	Molecular Function		Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	RRNA Transcription RRNA Metabolic Process Protein-containing Complex Assembly
Pathways		HATs acetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		7 interacting genes: ARID4B CCR9 CUL2 GPS1 MYC SMAD3 USP7	4 interacting genes: CEBPA MKI67 TNIP1 ZDHHC17
Entrez ID		79595	84365
HPRD ID		18015	17576
Ensembl ID		ENSG00000136715	ENSG00000155438
Uniprot IDs		A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3	Q9BYG3
PDB IDs			2AFF 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL6 8FL7 8FLA 8FLB 8FLD 8FLE 8INE 8INF 8IPX 8IPY 8IR3
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromatin Remodeling Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Intracellular Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization MAPK Cascade Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Positive Regulation Of MiRNA Transcription JNK Cascade Positive Regulation Of MiRNA Metabolic Process Regulation Of Intracellular Transport Epigenetic Regulation Of Gene Expression Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin Protein Ligase Binding Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of MiRNA Transcription T Cell Activation Regulation Of Stem Cell Population Maintenance Myc-Max Complex Regulation Of Acinar Cell Proliferation Regulation Of Cellular Response To Growth Factor Stimulus Sterol Response Element Binding Regulation Of MiRNA Metabolic Process Paraxial Mesoderm Morphogenesis Cis-regulatory Region Sequence-specific DNA Binding Apoptotic Signaling Pathway NK T Cell Proliferation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Symbiont-mediated Disruption Of Host Cell PML Body CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation	RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse CHOP-C/EBP Complex White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Inflammatory Response Rb-E2F Complex Positive Regulation Of Protein Deubiquitination Protein-cysteine S-myristoyltransferase Activity
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