FYCO1 and CDCP1

		FYCO1	CDCP1
Description		FYVE and coiled-coil domain autophagy adaptor 1	CUB domain containing protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Endosome Late Endosome Autophagosome Golgi Apparatus Membrane Cytoplasmic Vesicle	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Achilles tendon injury ( 33606446) Acne (severe) ( 24927181) Blood protein levels ( 30072576) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Macular thickness ( 30535121) Metabolite levels ( 23823483) Statin-induced myopathy (severe) ( 31220337)
Interacting Genes		4 interacting genes: APP KDM1A PRMT6 RAF1	6 interacting genes: CLK1 PLG PRKCD SDCBP SRC ST14
Entrez ID		79443	64866
HPRD ID		06215	16696
Ensembl ID		ENSG00000163820	ENSG00000163814
Uniprot IDs		Q9BQS8	Q9H5V8
PDB IDs		5CX3 5D94 7BQI
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Cellular Component Organization PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Neuron Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Lipoprotein Particle Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Microglia Development Glial Cell Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Death-inducing Signaling Complex Assembly Telomeric Repeat-containing RNA Binding Regulation Of Signal Transduction By P53 Class Mediator FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone H3R2 Methyltransferase Activity Histone H2AR3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Purine-containing Compound Chromatin Remodeling Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Cell Differentiation Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cell Maturation Regulation Of Protein Metabolic Process Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon	Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activator Activity Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Neutrophil Activation Fc-gamma Receptor Signaling Pathway Negative Regulation Of Coagulation Negative Regulation Of Blood Coagulation Negative Regulation Of Cell Adhesion Negative Regulation Of Hemostasis Positive Regulation Of Phosphate Metabolic Process Fc Receptor Signaling Pathway Enzyme Binding Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Blood Coagulation Negative Regulation Of Cell-substrate Adhesion Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Cellular Response To Hydrogen Peroxide Interleukin-5 Receptor Complex Azurophil Granule Lumen Protein Kinase Activity Regulation Of Cell-cell Adhesion Positive Regulation Of Sphingomyelin Catabolic Process Response To Hydrogen Peroxide Regulation Of Organelle Organization Cellular Response To Reactive Oxygen Species Positive Regulation Of Protein Localization To Nucleus Interleukin-5 Receptor Binding Positive Regulation Of Organelle Assembly Positive Regulation Of Organelle Organization Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Positive Regulation Of Cell Migration Blood Microparticle Positive Regulation Of Cell Motility Serine-type Peptidase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catabolic Process Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Myeloid Leukocyte Activation Positive Regulation Of Endodeoxyribonuclease Activity Termination Of Signal Transduction Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Epithelial Cell Morphogenesis Involved In Placental Branching Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Locomotion Regulation Of Wound Healing
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