LBHD1 and ARCN1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		LBHD1	ARCN1
Name		LBH domain containing 1	archain 1 coat protein complex I subunit delta
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Positive Regulation Of DNA-templated Transcription	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Adult Locomotory Behavior Protein Transport Vesicle-mediated Transport Cerebellar Purkinje Cell Layer Maturation Pigmentation Golgi Vesicle Transport Golgi Localization Establishment Of Localization In Cell
Pathways		None	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
GWAS		No GWAS studies recorded	Monocyte count ( 32888494 ) Monocyte percentage of white cells ( 32888494 )
Novel Interactors		None recorded	1 novel interactors: CXCR5
Interacting Genes		2 interacting genes: ARCN1 ERBB3	13 interacting genes: APP COPA COPB1 COPB2 COPG1 COPG2 COPZ2 DSCAM HMGB2 LBHD1 PDE4B TMED10 WBP2
Entrez ID		79081	372
HPRD ID		14499	02893
Ensembl ID		ENSG00000162194	ENSG00000095139
Uniprot IDs		Q9BQE6	B0YIW5 P48444
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Cerebellar Purkinje Cell Layer Maturation Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex ErbB-3 Class Receptor Binding Neuregulin Receptor Activity Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development COPI-coated Vesicle Membrane COPI-coated Vesicle Golgi Localization COPI Vesicle Coat Regulation Of Motor Neuron Apoptotic Process Negative Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process ERBB2-ERBB3 Signaling Pathway Schwann Cell Differentiation ERBB3 Signaling Pathway Protein Tyrosine Kinase Activator Activity Endocardial Cushion Development Schwann Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Striated Muscle Tissue Development ERBB2 Signaling Pathway Peripheral Nervous System Development Cranial Nerve Development Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Pigmentation Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Growth Factor Binding Regulation Of Striated Muscle Tissue Development Nerve Development Regulation Of Muscle Organ Development Positive Regulation Of Calcium-mediated Signaling Mesenchyme Development Glial Cell Development Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Lateral Plasma Membrane Wound Healing ERBB Signaling Pathway Adult Locomotory Behavior Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Calcium-mediated Signaling Myelination Axon Ensheathment Transport Vesicle Glial Cell Differentiation Neuron Apoptotic Process	COPI Vesicle Coat COPI-coated Vesicle Membrane Intra-Golgi Vesicle-mediated Transport Transport Vesicle Membrane Coat COPI-coated Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Cytoplasmic Vesicle Intracellular Protein Transport Structural Molecule Activity Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Golgi Apparatus Growth Cone Cellular Localization Establishment Of Localization In Cell Endoplasmic Reticulum Membrane Protein Transport RAGE Receptor Binding Golgi-associated Vesicle Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Chemotaxis Locomotion Intracellular Protein Localization Chemoattractant Activity Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cytokine Production Regulation Of CAMP/PKA Signal Transduction Positive Chemotaxis Neuron Recognition Cell Chemotaxis Secretion Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Microtubule-based Transport Amylin Binding Positive Regulation Of Toll Signaling Pathway Cytosol To ERGIC Protein Transport Cis-Golgi Network Protein Localization To ERGIC COPI-coated Vesicle Budding Positive Regulation Of Gene Expression, Epigenetic