ARCN1 and TMED10

Number of citations: 38 (PubMedID 9751720)
Data Source: BioGRID (pull down)

		ARCN1	TMED10
Name		archain 1 coat protein complex I subunit delta	transmembrane p24 trafficking protein 10
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Cytoplasmic Vesicle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Transport Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Gamma-secretase Complex
	Molecular Function	RNA Binding Protein Binding	Protein Binding Protein Transmembrane Transporter Activity Syntaxin Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Adult Locomotory Behavior Protein Transport Vesicle-mediated Transport Cerebellar Purkinje Cell Layer Maturation Pigmentation Golgi Vesicle Transport Golgi Localization Establishment Of Localization In Cell	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Vesicle-mediated Transport Positive Regulation Of Interleukin-1 Production Vesicle Cargo Loading COPI-coated Vesicle Budding Regulated Exocytosis Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Positive Regulation Of Protein Secretion Protein Transmembrane Transport Protein Localization To ERGIC Cytosol To ERGIC Protein Transport Regulation Of Amyloid-beta Formation
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
GWAS		Monocyte count ( 32888494 ) Monocyte percentage of white cells ( 32888494 )	Coronary artery disease ( 32469254 ) Heel bone mineral density ( 30598549 ) Height ( 19343178 ) Refractive error ( 32231278 )
Novel Interactors		1 novel interactors: CXCR5	2 novel interactors: NPC2 RGS6
Interacting Genes		13 interacting genes: APP COPA COPB1 COPB2 COPG1 COPG2 COPZ2 DSCAM HMGB2 LBHD1 PDE4B TMED10 WBP2	20 interacting genes: APH1A ARCN1 ARF1 CDC42 CEBPA COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 DHODH FBXO7 NCSTN NPSR1 PSENEN SEC23B SLC13A1 TMED2
Entrez ID		372	10972
HPRD ID		02893	12013
Ensembl ID		ENSG00000095139	ENSG00000170348
Uniprot IDs		B0YIW5 P48444	A0A024R6I3 P49755
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		COPI Vesicle Coat COPI-coated Vesicle Membrane Intra-Golgi Vesicle-mediated Transport Transport Vesicle Membrane Coat COPI-coated Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Cytoplasmic Vesicle Intracellular Protein Transport Structural Molecule Activity Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Golgi Apparatus Growth Cone Cellular Localization Establishment Of Localization In Cell Endoplasmic Reticulum Membrane Protein Transport RAGE Receptor Binding Golgi-associated Vesicle Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Chemotaxis Locomotion Intracellular Protein Localization Chemoattractant Activity Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cytokine Production Regulation Of CAMP/PKA Signal Transduction Positive Chemotaxis Neuron Recognition Cell Chemotaxis Secretion Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Microtubule-based Transport Amylin Binding Positive Regulation Of Toll Signaling Pathway Cytosol To ERGIC Protein Transport Cis-Golgi Network Protein Localization To ERGIC COPI-coated Vesicle Budding Positive Regulation Of Gene Expression, Epigenetic	COPI-coated Vesicle Membrane COPI Vesicle Coat Golgi Membrane Transport Vesicle COPI-coated Vesicle Intra-Golgi Vesicle-mediated Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Membrane Coat Endoplasmic Reticulum Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intracellular Transport Intracellular Protein Transport Golgi Apparatus Cytoplasmic Vesicle Vesicle-mediated Transport Cellular Localization Establishment Of Localization In Cell Establishment Of Protein Localization Protein Transport Gamma-secretase Complex Structural Molecule Activity Notch Receptor Processing Amyloid-beta Formation Intracellular Protein Localization Membrane Protein Intracellular Domain Proteolysis Golgi Localization Amyloid Precursor Protein Catabolic Process Endopeptidase Activator Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Amyloid-beta Metabolic Process Membrane Membrane Protein Proteolysis Notch Signaling Pathway Establishment Of Golgi Localization Endoplasmic Reticulum Golgi Cisterna Membrane Protein Localization To Axon Organelle Transport Along Microtubule Embryonic Placenta Development Protein Secretion Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Presynaptic Membrane Vesicle Cargo Loading Dendritic Spine Organization Mitotic Cleavage Furrow Ingression RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding