ARL5B

Description		ARF like GTPase 5B
Image
GO Annotations	Cellular Component	Cytoplasm Trans-Golgi Network
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Protein Localization To Golgi Membrane
Pathways
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Colorectal or endometrial cancer ( 26621817) Coronary artery disease in type 1 diabetes ( 29695241) Hepatitis C (spontaneous viral clearance) ( 33119750) Postoperative atrial fibrillation in coronary artery bypass grafting surgery ( 26385043) Suicide attempts in major depressive disorder ( 31164008)
Interacting Genes		2 interacting genes: FNDC11 SMAD4
Entrez ID		221079
HPRD ID		12328
Ensembl ID		ENSG00000165997
Uniprot IDs		B0YIW9 Q96KC2
PDB IDs		1YZG
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Metanephric Mesenchyme Morphogenesis SMAD Protein Complex Positive Regulation Of Luteinizing Hormone Secretion Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Atrioventricular Valve Formation Sebaceous Gland Development Heteromeric SMAD Protein Complex Formation Of Anatomical Boundary Brainstem Development Mesendoderm Development Sulfate Binding Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Transforming Growth Factor Beta2 Production Endocardial Cell Differentiation Atrioventricular Canal Development Somite Rostral/caudal Axis Specification Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Cardiac Muscle Cell Differentiation Endothelial Cell Activation Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Negative Regulation Of Cardiocyte Differentiation Secondary Palate Development Filamin Binding Neural Crest Cell Differentiation Heart Valve Formation Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cardiac Muscle Cell Apoptotic Process I-SMAD Binding Cardiac Conduction System Development Interleukin-6-mediated Signaling Pathway Gastrulation With Mouth Forming Second Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Cardiac Muscle Cell Differentiation Seminiferous Tubule Development Regulation Of Hair Follicle Development Regulation Of Extracellular Matrix Assembly Uterus Development Female Gonad Development Positive Regulation Of Extracellular Matrix Organization Outflow Tract Septum Morphogenesis SMAD Protein Signal Transduction Regulation Of Hair Cycle
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