NUP37 and NUP160

Number of citations of the paper that reports this interaction (PubMedID 35831314)
73

Data Source:
BioGRID (affinity chromatography technology, biochemical, two hybrid)

		NUP37	NUP160
Description		nucleoporin 37	nucleoporin 160
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Chromosome Cytosol Nuclear Pore Outer Ring	Kinetochore Nucleus Nuclear Envelope Nuclear Pore Cytosol Nuclear Pore Outer Ring
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Nucleocytoplasmic Transport Chromosome Segregation Protein Transport MRNA Transport Cell Division	MRNA Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Nephron Development
Pathways		ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation SARS-CoV-2 activates/modulates innate and adaptive immune responses	ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Central corneal thickness ( 32528159) General risk tolerance (MTAG) ( 30643258) Height ( 19893584 25429064) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278)	Alanine aminotransferase levels ( 33547301) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Aspartate aminotransferase levels ( 33547301) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Granulocyte percentage of myeloid white cells ( 27863252) Intraocular pressure ( 25173106 29235454 29617998) Liver enzyme levels (alkaline phosphatase) ( 33972514) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Neuroticism ( 29255261) Neutrophil percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Plateletcrit ( 27863252) Pulse pressure ( 30578418) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Sleep duration (short sleep) ( 30846698) Systolic blood pressure ( 30578418)
Interacting Genes		5 interacting genes: LNX1 NUP160 NUP43 TGFBR1 UBC	7 interacting genes: DISC1 ESRRG EXOSC1 KLHL20 NUP37 SUMO2 WEE2-AS1
Entrez ID		79023	23279
HPRD ID		14853	16254
Ensembl ID		ENSG00000075188	ENSG00000030066
Uniprot IDs		B4DKV8 Q8NFH4	A0A8V8NBT1 Q12769
PDB IDs		5A9Q 7PEQ 7R5J 7R5K	5A9Q 7PEQ 7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Nuclear Pore Outer Ring Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex RNA Transport MRNA Transport Kinetochore Nuclear Pore Positive Regulation Of Mesenchymal Stem Cell Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Myofibroblast Differentiation Activin Receptor Complex Activin Receptor Activity, Type I Ventricular Compact Myocardium Morphogenesis Parathyroid Gland Development Positive Regulation Of Tight Junction Disassembly Germ Cell Migration Transforming Growth Factor Beta Receptor Activity Trophoblast Cell Migration Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Transforming Growth Factor Beta Receptor Activity, Type I Nuclear Transport Nucleocytoplasmic Transport Nucleobase-containing Compound Transport Nuclear Envelope Coronary Artery Morphogenesis Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Type II Transforming Growth Factor Beta Receptor Binding Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Ubiquitin Protein Ligase Binding Coronary Vasculature Morphogenesis Activin Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Nephron Development Ventricular Trabecula Myocardium Morphogenesis Protein Tag Activity I-SMAD Binding Synapse Maturation Pharyngeal System Development Serine/threonine Protein Kinase Complex Heart Trabecula Morphogenesis Transforming Growth Factor Beta Binding Regulation Of Extracellular Matrix Assembly Structural Constituent Of Nuclear Pore Filopodium Assembly
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