NUP160

Description		nucleoporin 160
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GO Annotations	Cellular Component	Kinetochore Nucleus Nuclear Envelope Nuclear Pore Cytosol Nuclear Pore Outer Ring
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	MRNA Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Nephron Development
Pathways		ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Aspartate aminotransferase levels ( 33547301) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Granulocyte percentage of myeloid white cells ( 27863252) Intraocular pressure ( 25173106 29235454 29617998) Liver enzyme levels (alkaline phosphatase) ( 33972514) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Neuroticism ( 29255261) Neutrophil percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Plateletcrit ( 27863252) Pulse pressure ( 30578418) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Sleep duration (short sleep) ( 30846698) Systolic blood pressure ( 30578418)
Interacting Genes		7 interacting genes: DISC1 ESRRG EXOSC1 KLHL20 NUP37 SUMO2 WEE2-AS1
Entrez ID		23279
HPRD ID		16254
Ensembl ID		ENSG00000030066
Uniprot IDs		A0A8V8NBT1 Q12769
PDB IDs		5A9Q 7PEQ 7R5J 7R5K
Enriched GO Terms of Interacting Partners?
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