CACNB4 and TBL3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CACNB4	TBL3
Description		calcium voltage-gated channel auxiliary subunit beta 4	transducin beta like 3
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Voltage-gated Calcium Channel Complex Cytoplasmic Side Of Plasma Membrane Nuclear Speck Monoatomic Ion Channel Complex Synapse Presynapse Glutamatergic Synapse	Nucleus Nucleoplasm Nucleolus 90S Preribosome Small-subunit Processome
	Molecular Function	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Calcium Channel Activity Protein Binding Protein Kinase Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels	RNA Binding Protein Binding U3 SnoRNA Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Neuromuscular Junction Development Adult Walking Behavior Negative Regulation Of Cell Population Proliferation Gamma-aminobutyric Acid Secretion Neuronal Action Potential Propagation Monoatomic Ion Transmembrane Transport Synaptic Transmission, Glutamatergic Regulation Of Membrane Potential CAMP Metabolic Process Spleen Development Thymus Development Peyer's Patch Development T Cell Receptor Signaling Pathway Nervous System Process Detection Of Light Stimulus Involved In Visual Perception Muscle Cell Development Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Positive Regulation Of Protein Localization To Nucleolus Cellular Response To Leukemia Inhibitory Factor Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Synaptic Vesicle Exocytosis	Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Ribosomal Small Subunit Biogenesis
Pathways		Presynaptic depolarization and calcium channel opening NCAM1 interactions	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Nimodipine Spironolactone Nicardipine Magnesium sulfate Verapamil Levomenthol Nitrendipine Miconazole Amiodarone Mibefradil Dronedarone Nilvadipine Drotaverine Trimebutine Benidipine Cilnidipine Efonidipine Efonidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases		Episodic ataxias Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145) Idiopathic dilated cardiomyopathy ( 29495422) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		13 interacting genes: CACNA1A CBX3 CCDC102B CTBP2 EFHC2 FASLG MAP1A MED31 PTN REM1 SNCA SYT1 TBL3	12 interacting genes: AHR APPBP2 AURKB CACNB4 CUL4B DHX30 ITSN2 NR2E3 RNF10 SFN URM1 USP11
Entrez ID		785	10607
HPRD ID		09057	09327
Ensembl ID		ENSG00000182389	ENSG00000183751
Uniprot IDs		A0A1B0GTK1 A0A1B0GTP5 A0A1B0GTX8 E7DBM8 H0Y476 O00305	Q12788
PDB IDs		2D46	7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Modulation Of Chemical Synaptic Transmission Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Vesicle Fusion Regulation Of Dopamine Secretion Syntaxin Binding Synapse Transcription Coregulator Binding Regulation Of Synaptic Plasticity Dendrite Development Tau Protein Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Regulation Of Vesicle Fusion Positive Regulation Of SNARE Complex Assembly Regulation Of Catecholamine Secretion Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Neurotransmitter Secretion Synaptic Vesicle Exocytosis Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synchronous Neurotransmitter Secretion Cell-cell Signaling Signaling Cell Communication Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Chemical Synaptic Transmission Retrograde Axonal Protein Transport Primary Dendrite Dendrite Regeneration SNARE Binding Regulation Of Norepinephrine Uptake Regulation Of Amine Transport Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Syntaxin-3 Binding Calcium Ion Transmembrane Import Into Cytosol Retinal Cell Programmed Cell Death Trans-synaptic Signaling Synaptic Signaling Neuronal Cell Body Dendritic Branch Dendritic Microtubule Ossification Involved In Bone Remodeling Negative Regulation Of Serotonin Uptake Positive Regulation Of Exocytosis Transporter Regulator Activity Regulation Of Neurotransmitter Secretion Vesicle-mediated Transport In Synapse Negative Regulation Of Chaperone-mediated Autophagy Positive Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter	Post-translational Protein Modification Response To Light Stimulus Response To Radiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?