ZSCAN9 and FBXO17

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZSCAN9	FBXO17
Description		zinc finger and SCAN domain containing 9	F-box protein 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Glycoprotein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process ERAD Pathway
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Daytime nap ( 33568662) Familial squamous cell lung carcinoma ( 29924316) Fish- and plant-related diet ( 32066663) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	SAPHO syndrome ( 33816493)
Interacting Genes		15 interacting genes: AIRIM FBXO17 FHL2 GEM LMO3 MAGEH1 PRMT6 SP110 SRPK2 SUV39H1 TFF3 ZDHHC17 ZNF446 ZSCAN22 ZSCAN23	22 interacting genes: ADAMTSL4 ADRB2 CBY2 CDCA8 DZIP3 EIF4H JRK KPRP KRT75 KRTAP13-2 LASP1 OAS2 PTPN21 RAB11FIP2 RUNX1 SAXO1 SAXO2 SKP1 USP54 ZNF213 ZNF829 ZSCAN9
Entrez ID		7746	115290
HPRD ID		03766	16436
Ensembl ID		ENSG00000137185	ENSG00000269190
Uniprot IDs		A0A0B4J224 O15535	Q96EF6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Histone Methyltransferase Activity Histone H3 Methyltransferase Activity Nucleus Perforant Pathway To Dendrate Granule Cell Synapse Histone H2AR3 Methyltransferase Activity Atrial Cardiac Muscle Cell Development Regulation Of Gene Expression Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Histone H3R2 Methyltransferase Activity Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Regulation Of Macromolecule Biosynthetic Process
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