FBXO17 and SAXO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FBXO17	SAXO2
Description		F-box protein 17	stabilizer of axonemal microtubules 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Centriole Cytoskeleton Axonemal Microtubule Ciliary Basal Body Sperm Flagellum
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Microtubule Binding
	Biological Process	Glycoprotein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process ERAD Pathway
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		SAPHO syndrome ( 33816493)	Feeling fed-up ( 29500382)
Interacting Genes		22 interacting genes: ADAMTSL4 ADRB2 CBY2 CDCA8 DZIP3 EIF4H JRK KPRP KRT75 KRTAP13-2 LASP1 OAS2 PTPN21 RAB11FIP2 RUNX1 SAXO1 SAXO2 SKP1 USP54 ZNF213 ZNF829 ZSCAN9	2 interacting genes: FBXO17 FHL2
Entrez ID		115290	283726
HPRD ID		16436	16817
Ensembl ID		ENSG00000269190	ENSG00000188659
Uniprot IDs		Q96EF6	A0A804HKW2 Q658L1
PDB IDs
Enriched GO Terms of Interacting Partners?			Atrial Cardiac Muscle Cell Development Negative Regulation Of Calcineurin-NFAT Signaling Cascade Heart Trabecula Formation Ventricular Cardiac Muscle Cell Development Negative Regulation Of Calcium-mediated Signaling Transcription Factor Binding BHLH Transcription Factor Binding Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Cardiac Muscle Cell Development Glycoprotein Catabolic Process Cardiac Cell Development SCF Ubiquitin Ligase Complex SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
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