RNF112 and FOXM1

Number of citations of the paper that reports this interaction (PubMedID 37288663)
63

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		RNF112	FOXM1
Description		ring finger protein 112	forkhead box M1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Synaptic Vesicle Postsynaptic Density Membrane Nuclear Body Cytoplasmic Vesicle Cell Projection Neuron Projection Perikaryon Cell Body Synapse	Chromatin Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Kinase Binding Sequence-specific DNA Binding
	Biological Process	Endoplasmic Reticulum Organization Nervous System Development Protein Ubiquitination Neuron Differentiation Response To Hydroperoxide Positive Regulation Of Neuron Differentiation Positive Regulation Of Glial Cell Differentiation Protein Homooligomerization Regulation Of Cell Cycle Protein Autoubiquitination G1 To G0 Transition Involved In Cell Differentiation Embryonic Brain Development	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Population Proliferation DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Cell Population Proliferation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Ras Protein Signal Transduction Regulation Of Cell Cycle Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Double-strand Break Repair
Pathways			Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS			Height ( 31562340)
Interacting Genes		1 interacting genes: FOXM1	22 interacting genes: BANP CCNE1 CDK1 CDK2 CDK4 CDK6 CHEK2 CREBBP DCAF1 LINC00857 MTDH OS9 RB1 RNF112 SIRT1 STAT3 SUMO1 UBE2I UCHL3 USP21 USP7 ZBTB3
Entrez ID		7732	2305
HPRD ID		03140	03823
Ensembl ID		ENSG00000128482	ENSG00000111206
Uniprot IDs		Q9ULX5	A0A0D9SFF0 A0A2P9DTZ0 A0A2P9DTZ1 A0A2P9DTZ8 A8K591 Q08050 Q53Y49
PDB IDs			3G73 7FJ2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Stress-activated MAPK Cascade Cell Cycle G2/M Phase Transition DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Ras Protein Signal Transduction G2/M Transition Of Mitotic Cell Cycle Regulation Of Stress-activated MAPK Cascade	Post-translational Protein Modification Mitotic Cell Cycle Phase Transition Protein Modification Process Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cyclin-dependent Protein Kinase Holoenzyme Complex PML Body Negative Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division Cyclin Binding Protein Modification By Small Protein Conjugation Regulation Of Mitotic Cell Cycle DNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Deubiquitination Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Nuclear Body Negative Regulation Of RNA Metabolic Process Positive Regulation Of Cell Cycle Phase Transition Protein Modification By Small Protein Removal Negative Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Phase Transition Chromatin Remodeling Protein Metabolic Process Regulation Of Gene Expression Regulation Of Cell Cycle Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process DNA Repair Nucleus Regulation Of Primary Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Response Protein Serine Kinase Activity Negative Regulation Of Cell Cycle Positive Regulation Of Catabolic Process Cyclin E1-CDK2 Complex Cyclin-dependent Protein Kinase Activity
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