ZNF148 and IFT122

		ZNF148	IFT122
Description		zinc finger protein 148	intraflagellar transport 122
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Cilium Membrane Intraciliary Transport Particle A Nuclear Membrane Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Ciliary Tip Non-motile Cilium
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Gamete Generation Negative Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Neural Tube Closure Embryonic Body Morphogenesis Spinal Cord Dorsal/ventral Patterning Cell Projection Organization Embryonic Heart Tube Development Embryonic Forelimb Morphogenesis Intracellular Signal Transduction Intraciliary Anterograde Transport Intraciliary Retrograde Transport Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Camera-type Eye Morphogenesis Limb Development Cilium Assembly Embryonic Heart Tube Left/right Pattern Formation Protein Localization To Cilium Establishment Of Protein Localization To Organelle Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases			Cranioectodermal dysplasia
GWAS		Urate levels ( 31578528)	A body shape index ( 34021172) Diisocyanate-induced asthma ( 25918132) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		25 interacting genes: CAVIN1 CEP63 CEP70 CLK1 DEUP1 EP300 GLRX3 GORASP2 JADE1 KRT31 KRT34 LNX1 LNX2 NUTM2F PFDN5 PLEKHG4 PNMA1 POU6F2 SIAH1 STAT3 TP53 TRIM10 UBC USP54 ZMYND12	2 interacting genes: DSCAM DSCR9
Entrez ID		7707	55764
HPRD ID		03540	06922
Ensembl ID		ENSG00000163848	ENSG00000163913
Uniprot IDs		Q9UQR1	A0A8I5KSG5 A0A8I5KT04 A0A8I5KTL4 A0A8I5KUU2 A0A8I5KVC7 A0A8I5KWK4 A0A8I5KXT5 A0A8I5QKR8 A0A8I5QKX8 A0A8J9A3C6 B3KUD1 B4DST2 Q9HBG6
PDB IDs			8BBE 8BBF 8BBG 8FGW 8FH3
Enriched GO Terms of Interacting Partners?		T Cell Lineage Commitment De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Negative Regulation Of MiRNA Processing Regulation Of Carbohydrate Catabolic Process Regulation Of Purine Nucleotide Metabolic Process T-helper 17 Cell Lineage Commitment Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Regulation Of Regulatory NcRNA Processing T-helper Cell Lineage Commitment CD4-positive, Alpha-beta T Cell Lineage Commitment System Development Organelle Organization Histone Acetyltransferase Complex CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Autophagy Negative Regulation Of Small Molecule Metabolic Process Organelle Assembly Alpha-beta T Cell Lineage Commitment Identical Protein Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing RRNA Transcription Centriole Replication Centriole Assembly Regulation Of Generation Of Precursor Metabolites And Energy Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Peptidyl-lysine Propionylation Nervous System Development Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity RNA Polymerase III Assembly RNA Polymerase I Assembly Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Cell Differentiation Cellular Component Assembly	Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding
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