ZNF3 and ID3

Number of citations of the paper that reports this interaction (PubMedID 18255255)
0

Data Source:
BioGRID (two hybrid)

		ZNF3	ID3
Description		zinc finger protein 3	inhibitor of DNA binding 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Protein Dimerization Activity Transcription Regulator Inhibitor Activity Leptomycin B Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Leukocyte Activation	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Leptomycin B
Pathways		Generic Transcription Pathway	NGF-stimulated transcription
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: CRYAA FHL2 GOLGA2 GRSF1 ID3 KRT27 LMNA LZTS1 MCC MTUS2 NDEL1 SF3B4 SSX2IP TRAF4 YJU2B ZNF212	49 interacting genes: ADD1 ANKS1A ATF3 BOLA2 BOLA2B C22orf39 CBFA2T2 CDK2 CNOT3 CREB5 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 FRS3 GATA4 GNB2 GTF2A1L GUCD1 HES1 HOXA1 ID4 IFI16 IKBKG KAT5 KRTAP26-1 LMO4 MLX MSGN1 MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SDCBP SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		7551	3399
HPRD ID		01911	02608
Ensembl ID		ENSG00000166526	ENSG00000117318
Uniprot IDs		B3KRP4 P17036 Q86U76	Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?		Ventricular Cardiac Muscle Cell Development	Protein Dimerization Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding E-box Binding Chromatin RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Cellular Developmental Process Nucleus Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Cell Differentiation Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Skeletal Muscle Cell Differentiation Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Skeletal Muscle Fiber Development Nucleoplasm Positive Regulation Of Metabolic Process Transcription Regulator Complex Cell Fate Commitment Negative Regulation Of Macromolecule Biosynthetic Process Muscle Cell Fate Commitment Positive Regulation Of Macromolecule Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Biosynthetic Process Positive Regulation Of Myoblast Differentiation Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development
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