TUFT1 and ABCD3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		TUFT1	ABCD3
Description		tuftelin 1	ATP binding cassette subfamily D member 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region RNA Polymerase II, Core Complex Cytoplasm I Band	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis Structural Constituent Of Tooth Enamel	Nucleotide Binding Long-chain Fatty Acid Transmembrane Transporter Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity Identical Protein Binding Protein Homodimerization Activity Fatty Acyl-CoA Hydrolase Activity ABC-type Transporter Activity
	Biological Process	Bone Mineralization Biomineral Tissue Development Odontogenesis	Very Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Lipid Transport Peroxisome Organization Response To Xenobiotic Stimulus Bile Acid And Bile Salt Transport Long-chain Fatty Acid Import Into Peroxisome Very Long-chain Fatty Acid Catabolic Process Transmembrane Transport Phytanic Acid Metabolic Process
Pathways			ABC transporters in lipid homeostasis RHOA GTPase cycle RHOC GTPase cycle Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		11 interacting genes: ABCD3 BIRC2 CCDC33 CEP76 KAT5 LMO2 LMO3 NME7 TFIP11 TRIM27 ZYX	7 interacting genes: ABCD1 ABCD2 COL6A2 PEX19 PSMA1 TUFT1 UBC
Entrez ID		7286	5825
HPRD ID		02516	01368
Ensembl ID		ENSG00000143367	ENSG00000117528
Uniprot IDs		B7Z4Y1 Q9NNX1	P28288
PDB IDs			8Z0F 8Z9X
Enriched GO Terms of Interacting Partners?		Transcription Coactivator Activity	Peroxisomal Membrane Transport Organophosphate Ester Transmembrane Transporter Activity Nucleobase-containing Compound Transmembrane Transporter Activity Peroxisome Organization Sulfur Compound Transmembrane Transporter Activity Amide Transmembrane Transporter Activity Long-chain Fatty Acid Import Into Peroxisome Fatty Acid Beta-oxidation Peroxisomal Membrane Very Long-chain Fatty Acid Catabolic Process Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Unsaturated Fatty Acid Biosynthetic Process Neuron Projection Maintenance Positive Regulation Of Fatty Acid Oxidation Fatty Acyl-CoA Hydrolase Activity Myelin Maintenance Alpha-linolenic Acid Metabolic Process Peroxisome Long-chain Fatty Acid Transmembrane Transporter Activity Regulation Of Fatty Acid Beta-oxidation Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Lipid Modification Linoleic Acid Metabolic Process Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipid Catabolic Process ATPase-coupled Transmembrane Transporter Activity Regulation Of Fatty Acid Oxidation Carboxylic Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Intracellular Lipid Transport Long-chain Fatty Acid Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Fatty Acid Metabolic Process ABC-type Transporter Activity Regulation Of Reactive Oxygen Species Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Neuron Projection Organization Lipid Catabolic Process Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Fatty Acid Biosynthetic Process Long-chain Fatty Acid Transport Fatty Acid Derivative Biosynthetic Process Fatty Acid Metabolic Process Regulation Of Lipid Catabolic Process Regulation Of Small Molecule Metabolic Process Very Long-chain Fatty-acyl-CoA Catabolic Process ABC-type Fatty-acyl-CoA Transporter Activity
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