TNR and QSOX1

		TNR	QSOX1
Description		tenascin R	quiescin sulfhydryl oxidase 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Extracellular Matrix Membrane Raft Perineuronal Net Tenascin Complex Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen
	Molecular Function		Protein Disulfide Isomerase Activity Oxidoreductase Activity Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity FAD Binding
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Nervous System Development Axon Guidance Associative Learning Negative Regulation Of Neuron Projection Development Telencephalon Cell Migration Negative Regulation Of Cell-cell Adhesion Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Negative Regulation Of Axon Extension Synaptic Transmission, Glutamatergic Locomotory Exploration Behavior Regulation Of Cell Differentiation Axon Extension Axon Extension Involved In Regeneration Negative Regulation Of Axon Extension Involved In Regeneration Modulation Of Chemical Synaptic Transmission Negative Regulation Of Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Transmission Of Nerve Impulse Long-term Synaptic Potentiation Neuroblast Migration	Protein Folding Negative Regulation Of Macroautophagy Extracellular Matrix Assembly
Pathways		ECM proteoglycans	Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Attention deficit hyperactivity disorder ( 30563984) Body mass index ( 26426971) Corneal astigmatism ( 29422769) Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644) Liver fibrosis in non-alcoholic fatty liver disease ( 31311600) Sleep (1/2-day periodicity) ( 33075057) Telomere length ( 30185882) Testosterone levels x fluid intelligence interaction ( 33407712) Tonometry ( 17903302)	Anorexia nervosa ( 23568457) Pulse pressure ( 30224653 30578418)
Interacting Genes		16 interacting genes: ACAN BCAN CCDC146 CNTN1 LGALS14 MAGEB4 NCAN NCK2 NFASC NTAQ1 POLR3C PSMA1 PTPRZ1 SIGLEC1 TRIM54 VCAN	7 interacting genes: BEGAIN CCR1 CCR6 CHRM4 SHANK3 UBE2D2 UBQLN4
Entrez ID		7143	5768
HPRD ID		03589	06785
Ensembl ID		ENSG00000116147	ENSG00000116260
Uniprot IDs		A1L306 Q92752	A0A140VKE5 O00391
PDB IDs		8FN9 8FNA	3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?		Perineuronal Net Carbohydrate Binding Hyaluronic Acid Binding Central Nervous System Development Lysosomal Lumen Golgi Lumen Cell Adhesion Synapse Skeletal System Development Extracellular Matrix Structural Constituent Conferring Compression Resistance System Development Cell-cell Adhesion Mediator Activity Extracellular Matrix Clathrin-dependent Endocytosis Of Virus By Host Cell Protein-N-terminal Glutamine Amidohydrolase Activity	G Protein-coupled Receptor Activity Chemokine Receptor Activity Dendritic Cell Migration Dendritic Cell Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Positive Regulation Of Synaptic Transmission Regulation Of Neuron Projection Regeneration Positive Regulation Of Synaptic Transmission, Glutamatergic
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