QSOX1

Description		quiescin sulfhydryl oxidase 1
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Protein Disulfide Isomerase Activity Oxidoreductase Activity Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity FAD Binding
	Biological Process	Protein Folding Negative Regulation Of Macroautophagy Extracellular Matrix Assembly
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Pulse pressure ( 30224653 30578418)
Novel Interacting Genes		9 novel interacting genes: AKIP1 CREG1 GPR52 GREM2 KIF5B PHAF1 PRRX1 SERPINC1 TNR
Interacting Genes		7 interacting genes: BEGAIN CCR1 CCR6 CHRM4 SHANK3 UBE2D2 UBQLN4
Entrez ID		5768
HPRD ID		06785
Ensembl ID		ENSG00000116260
Uniprot IDs		A0A140VKE5 O00391
PDB IDs		3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity Chemokine Receptor Activity Dendritic Cell Migration Dendritic Cell Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Positive Regulation Of Synaptic Transmission Regulation Of Neuron Projection Regeneration Positive Regulation Of Synaptic Transmission, Glutamatergic
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