SSR2 and SRPR

Number of citations of the paper that reports this interaction (PMID 3021779)
45

Data Source:
HPRD (in vitro, in vivo)

		SSR2	SRPR
Gene Name		signal sequence receptor, beta (translocon-associated protein beta)	signal recognition particle receptor (docking protein)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function		GTPase Activity Signal Recognition Particle Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Cellular Protein Metabolic Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Gene Expression Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane	IRE1alpha activates chaperones Translation SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: SRPR	3 interactors: RPL10A RUSC2 SSR2
Entrez ID		6746	6734
HPRD ID		02923	01645
Ensembl ID		ENSG00000163479	ENSG00000182934
Uniprot IDs		P43308	P08240
PDB IDs			2FH5 2GO5
Enriched GO Terms of Interacting Partners?		Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Endoplasmic Reticulum Unfolded Protein Response SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Cellular Response To Unfolded Protein Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Protein Localization To Endoplasmic Reticulum Response To Unfolded Protein Response To Endoplasmic Reticulum Stress Protein Targeting To Membrane	SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Organelle Protein Localization To Membrane Protein Targeting Protein Localization To Organelle Translation Cytoplasmic Transport Membrane Organization Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Viral Transcription Intracellular Transport Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Tagcloud ?		anticancer barrier bcrp candidate characterization clarify coil coiled ddrt display dutpase efflux encoding hsp105 inducible insight mdr multidrug osteosarcoma osteosarcomas parental pump rb1 rb1cc1 retinoblastoma successful transmembrane variant yield	ap2b2 ap3d1and cho correlating ddb1 dhfr displaying division doubling exposing extrinsic hamster intrinsic landscape mthfd2 ovary pca polarity principal productivity proteomics ranked rcan1 shotgun technologies tmem20 top traits transcriptomics
Tagcloud (Difference) ?		anticancer barrier bcrp candidate characterization clarify coil coiled ddrt display dutpase efflux encoding hsp105 inducible insight mdr multidrug osteosarcoma osteosarcomas parental pump rb1 rb1cc1 retinoblastoma successful transmembrane variant yield	ap2b2 ap3d1and cho correlating ddb1 dhfr displaying division doubling exposing extrinsic hamster intrinsic landscape mthfd2 ovary pca polarity principal productivity proteomics ranked rcan1 shotgun technologies tmem20 top traits transcriptomics
Tagcloud (Intersection) ?