FAM228A and PLEKHA7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM228A	PLEKHA7
Description		family with sequence similarity 228 member A	pleckstrin homology domain containing A7
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Zonula Adherens Cell Junction Pore Complex Extracellular Exosome Anchoring Junction
	Molecular Function	Protein Binding	Protein Binding Delta-catenin Binding
	Biological Process		Cell-cell Adhesion Mediated By Cadherin Zonula Adherens Maintenance Pore Complex Assembly Epithelial Cell-cell Adhesion Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		White blood cell count ( 32888494)	Blood pressure ( 21909110) Blood protein levels ( 30072576) Body mass index ( 26426971) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27618452 27841878 19430479 28739976) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary angle closure) ( 22922875 27064256) Glaucoma (primary open-angle) ( 33627673) Intraocular pressure ( 31959993 29617998 29785010 30054594) Macular thickness ( 30535121) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Microalbuminuria in type 1 diabetes ( 31537649) Systolic blood pressure ( 30578418 28739976 27841878 27618452 19430479) Systolic blood pressure change trajectory ( 27980656) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		18 interacting genes: BYSL CCDC57 CDKN2D COX5B EAF1 ENKD1 FAM90A1 GYS1 HSF2BP LMO2 LMO4 MLH1 PLEKHA7 SAT1 SCNM1 SPANXN3 TNS2 ZNF76	20 interacting genes: B9D2 CCHCR1 CCNDBP1 FAM228A GRB2 HOMEZ HSF2BP IGFBP6 IGFL2 LZTS1 NEK6 PIBF1 PICK1 PPL RDH12 RHOH STMN3 TRAF4 TSGA10 ZMAT5
Entrez ID		653140	144100
HPRD ID		19048	15142
Ensembl ID		ENSG00000186453	ENSG00000166689
Uniprot IDs		Q86W67	A0A8V8TMS3 E9PKC0 Q6IQ23
PDB IDs			7KJO 7KJZ 7KK7
Enriched GO Terms of Interacting Partners?
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