PLEKHA7 and IGFL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLEKHA7	IGFL2
Description		pleckstrin homology domain containing A7	IGF like family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Zonula Adherens Cell Junction Pore Complex Extracellular Exosome Anchoring Junction	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Delta-catenin Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Cell-cell Adhesion Mediated By Cadherin Zonula Adherens Maintenance Pore Complex Assembly Epithelial Cell-cell Adhesion Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Blood protein levels ( 30072576) Body mass index ( 26426971) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27618452 27841878 19430479 28739976) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary angle closure) ( 22922875 27064256) Glaucoma (primary open-angle) ( 33627673) Intraocular pressure ( 31959993 29617998 29785010 30054594) Macular thickness ( 30535121) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Microalbuminuria in type 1 diabetes ( 31537649) Systolic blood pressure ( 30578418 28739976 27841878 27618452 19430479) Systolic blood pressure change trajectory ( 27980656) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		20 interacting genes: B9D2 CCHCR1 CCNDBP1 FAM228A GRB2 HOMEZ HSF2BP IGFBP6 IGFL2 LZTS1 NEK6 PIBF1 PICK1 PPL RDH12 RHOH STMN3 TRAF4 TSGA10 ZMAT5	3 interacting genes: PITX1 PLEKHA7 TLX3
Entrez ID		144100	147920
HPRD ID		15142	13729
Ensembl ID		ENSG00000166689	ENSG00000204866
Uniprot IDs		A0A8V8TMS3 E9PKC0 Q6IQ23	Q6UWQ7
PDB IDs		7KJO 7KJZ 7KK7
Enriched GO Terms of Interacting Partners?			Branchiomeric Skeletal Muscle Development Myoblast Fate Commitment Zonula Adherens Maintenance Regulation Of Respiratory Gaseous Exchange By Nervous System Process GABAergic Neuron Differentiation Pore Complex Zonula Adherens Adherens Junction Maintenance Delta-catenin Binding Sequence-specific Double-stranded DNA Binding Regulation Of Respiratory System Process Epithelial Cell-cell Adhesion Pore Complex Assembly DNA-binding Transcription Factor Activity Embryonic Hindlimb Morphogenesis Pituitary Gland Development Respiratory Gaseous Exchange By Respiratory System Neuron Fate Specification Regulation Of Respiratory Gaseous Exchange Cell-cell Junction Maintenance Hindlimb Morphogenesis Cell-cell Adhesion Mediated By Cadherin Cell Junction Maintenance Adherens Junction Organization
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