BCL11B and C14orf132

		BCL11B	C14orf132
Description		BCL11 transcription factor B	chromosome 14 open reading frame 132
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus SWI/SNF Complex Neuron Projection	Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Keratinocyte Development Epithelial Cell Morphogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Apoptotic Process Axonogenesis Negative Regulation Of Cell Population Proliferation Post-embryonic Development Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Regulation Of Lipid Metabolic Process Striatal Medium Spiny Neuron Differentiation Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Central Nervous System Neuron Differentiation Post-embryonic Camera-type Eye Development T Cell Differentiation In Thymus T Cell Receptor V(D)J Recombination Hematopoietic Stem Cell Migration Odontogenesis Of Dentin-containing Tooth Positive T Cell Selection Skin Development Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Alpha-beta T Cell Differentiation Thymus Development T Cell Apoptotic Process Negative Regulation Of T Cell Apoptotic Process Thymocyte Apoptotic Process Negative Regulation Of Thymocyte Apoptotic Process Olfactory Bulb Axon Guidance Lymphoid Lineage Cell Migration Into Thymus
Pathways		Formation of the embryonic stem cell BAF (esBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Airway wall thickness ( 25517131) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Aortic stiffness ( 22068335) Bipolar disorder ( 34002096 31043756) Brain morphology (MOSTest) ( 32665545) Corneal curvature ( 22969067) Diastolic blood pressure night-to-day ratio in hypertension ( 29973135) Hematocrit ( 32888494) Hemoglobin ( 32888494) Medial thalamic nuclei volume ( 34006833) Metabolite levels ( 23823483) Posterior thalamic nuclei volume ( 34006833) Proximal colorectal cancer ( 33632709) Red blood cell count ( 32888494) Schizophrenia ( 30285260 29483656 28991256 25056061) Staphylococcus aureus infection ( 24847357) Systolic blood pressure night-to-day ratio in hypertension ( 29973135) Triglyceride levels in HIV infection ( 33109212) Waist circumference ( 34074324)	Cerebrospinal fluid AB1-42 levels ( 28247064) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Erectile dysfunction ( 30583798) Mumps ( 28928442)
Interacting Genes		5 interacting genes: CBX5 NR2F1 NR2F2 SP1 SUV39H1
Entrez ID		64919	56967
HPRD ID		05950	16603
Ensembl ID		ENSG00000127152	ENSG00000227051
Uniprot IDs		L8B567 L8B7P7 L8B862 L8B8F6 Q9C0K0	A0A1B0GU51 A0A1B0GWH2 Q9NPU4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Transcription Repressor Complex Cellular Response To Wortmannin Heterochromatin Nuclear Receptor Activity Radial Pattern Formation Evoked Excitatory Postsynaptic Potential Negative Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Response To Wortmannin Histone Deacetylase Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Cellular Response To Zinc Ion Starvation Regulation Of Endothelial Cell Proliferation Histone H3K9 Trimethyltransferase Activity Chromosome, Centromeric Region Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Gene Expression, Epigenetic Heterochromatin Formation ENoSc Complex RDNA Heterochromatin Negative Regulation Of RNA Biosynthetic Process Lymphatic Endothelial Cell Fate Commitment Cellular Response To Starvation Negative Regulation Of Nucleobase-containing Compound Metabolic Process RDNA Heterochromatin Formation Retinoic Acid-responsive Element Binding Regulation Of Endothelial Cell Migration Histone H3K9me2 Methyltransferase Activity Regulation Of Transcription By Glucose Response To Starvation Histone H3K9 Methyltransferase Activity Intracellular Receptor Signaling Pathway Maternal Placenta Development Regulation Of DNA-templated Transcription Transcription Cis-regulatory Region Binding Rhythmic Process Regulation Of RNA Biosynthetic Process Cellular Response To Nutrient Levels Nuclear Lamina Facultative Heterochromatin Formation Epigenetic Regulation Of Gene Expression Epigenetic Programming In The Zygotic Pronuclei Chromatin Silencing Complex DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Lymph Vessel Development Trophoblast Giant Cell Differentiation Interneuron Migration	Neuron Projection Guidance Axon Guidance Olfactory Bulb Axon Guidance Lymphoid Lineage Cell Migration Into Thymus T Cell Receptor V(D)J Recombination Post-embryonic Camera-type Eye Development Striatal Medium Spiny Neuron Differentiation Neuron Projection Development Animal Organ Morphogenesis Negative Regulation Of Ruffle Assembly Forebrain Neuron Fate Commitment Hematopoietic Stem Cell Migration Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Negative Regulation Of Thymocyte Apoptotic Process Profilin Binding Thymocyte Apoptotic Process Keratinocyte Development GABAergic Neuron Differentiation Regulation Of Thymocyte Apoptotic Process Positive T Cell Selection Negative Regulation Of Epithelial Cell Migration V(D)J Recombination Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of T Cell Apoptotic Process Regulation Of Ruffle Assembly SWI/SNF Complex T Cell Apoptotic Process T Cell Selection Cell Projection Organization Lymphocyte Apoptotic Process Epithelial Cell Morphogenesis Negative Regulation Of Lymphocyte Apoptotic Process Forebrain Neuron Differentiation Neuron Fate Commitment Regulation Of T Cell Apoptotic Process Positive Regulation Of Actin Filament Polymerization Regulation Of Keratinocyte Proliferation Leukocyte Apoptotic Process Somatic Cell DNA Recombination Thymus Development T Cell Differentiation In Thymus Positive Regulation Of Stress Fiber Assembly Skin Development Actin Polymerization Or Depolymerization Negative Regulation Of Leukocyte Apoptotic Process Protein Homotetramerization Anatomical Structure Morphogenesis Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Lymphocyte Apoptotic Process Regulation Of Epithelial Cell Migration
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