MTARC1 and NAA11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MTARC1	NAA11
Description		mitochondrial amidoxime reducing component 1	N-alpha-acetyltransferase 11, NatA catalytic subunit
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane Nitric-oxide Synthase Complex	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Cilium NatA Complex Ciliary Basal Body
	Molecular Function	Catalytic Activity Protein Binding Nitrate Reductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Molybdenum Ion Binding Pyridoxal Phosphate Binding Molybdopterin Cofactor Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity Nitrite Reductase Activity	Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Binding Protein-N-terminal-alanine Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity
	Biological Process	Nitric Oxide Biosynthetic Process Nitrate Metabolic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound	N-terminal Protein Amino Acid Acetylation
Pathways		Phase I - Functionalization of compounds
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Refractive error ( 32231278) Schizophrenia ( 33169155)
Interacting Genes		2 interacting genes: EPHB6 NAA11	15 interacting genes: ACOT12 AP2M1 BAALC CDC25A CDCA5 CREBRF EHMT2 HIF1A KIFAP3 MTARC1 NAA15 NAA16 TOM1 ZBTB14 ZNF202
Entrez ID		64757	84779
HPRD ID		08653	19248
Ensembl ID		ENSG00000186205	ENSG00000156269
Uniprot IDs		Q5VT66	Q9BSU3
PDB IDs		6FW2
Enriched GO Terms of Interacting Partners?		Detoxification Of Zinc Ion Manganese Ion Export Across Plasma Membrane Calcium:manganese Antiporter Activity Isoleucine-tRNA Ligase Activity Isoleucyl-tRNA Aminoacylation Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Patched Ligand Maturation Protein N-terminal-serine Acetyltransferase Activity Manganese Ion Transmembrane Transporter Activity Intracellular Manganese Ion Homeostasis Manganese Ion Homeostasis Protein-N-terminal Amino-acid Acetyltransferase Activity NatA Complex Zinc Ion Import Into Organelle Manganese Ion Transmembrane Transport Manganese Ion Transport Aminoacyl-tRNA Metabolism Involved In Translational Fidelity Aminoacyl-tRNA Deacylase Activity 9+0 Non-motile Cilium Regulation Of Response To Drug N-terminal Protein Amino Acid Acetylation Diaphragm Development Molecular Carrier Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Cellular Response To Angiotensin Intracellular Copper Ion Homeostasis Monoatomic Cation Transmembrane Transporter Activity Regulation Of Translational Fidelity Protein Maturation Copper Ion Homeostasis Skeletal Muscle Organ Development	NatA Complex Nuclear Body Negative Regulation Of Thymocyte Apoptotic Process Regulation Of Thymocyte Apoptotic Process Acetyltransferase Activator Activity N-terminal Protein Amino Acid Acetylation Acetyltransferase Activity Negative Regulation Of T Cell Apoptotic Process Protein Acetylation Transcription Corepressor Binding Regulation Of Neuroblast Proliferation Negative Regulation Of Lymphocyte Apoptotic Process Regulation Of T Cell Apoptotic Process Regulation Of Macroautophagy Neuroblast Proliferation Histone H3K56 Methyltransferase Activity Positive Regulation Of Calcium-dependent Cell-cell Adhesion Positive Regulation Of Prolactin Signaling Pathway Negative Regulation Of Leukocyte Apoptotic Process Transcription Regulator Complex Regulation Of Lymphocyte Apoptotic Process
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