CTAGE1 and CEP192

		CTAGE1	CEP192
Description		cutaneous T cell lymphoma-associated antigen 1	centrosomal protein 192
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Exit Site	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Procentriole Procentriole Replication Complex
	Molecular Function		Protein Binding Phosphatase Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Secretion Vesicle Cargo Loading	Centrosome Cycle Centriole Replication Response To Bacterium Centrosome Duplication Protein Localization To Centrosome Centrosome-templated Microtubule Nucleation Mitotic Spindle Assembly
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Abdominal aortic aneurysm ( 32981348) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Coronary artery disease ( 29212778 33020668) Diastolic blood pressure ( 30224653) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Lung function (FEV1) ( 30061609) Moyamoya disease ( 29273593) Myocardial infarction ( 33532862) Resting heart rate ( 27798624) Triglyceride levels ( 32203549) Tuberculosis ( 20694014) Urate levels in overweight individuals ( 25811787)	Appendicular lean mass ( 33097823) General cognitive ability ( 29844566)
Interacting Genes			5 interacting genes: CIP2A LINC00839 PPP1CA SHBG UBC
Entrez ID		64693	55125
HPRD ID		16395	10855
Ensembl ID		ENSG00000212710	ENSG00000101639
Uniprot IDs		Q8NEG8 Q96RT6	Q8TEP8
PDB IDs			4N7Z 6FVI 6W3J 7PTB 8GUW 8PR7
Enriched GO Terms of Interacting Partners?		Procentriole Centrosome-templated Microtubule Nucleation Microtubule Nucleation By Microtubule Organizing Center Procentriole Replication Complex Centriole Assembly Microtubule Nucleation Centriole Replication Pericentriolar Material Protein Localization To Centrosome Centrosome Duplication Phosphatase Binding Centrosome Cycle Mitotic Spindle Assembly Protein Localization To Cytoskeleton Microtubule Organizing Center Organization Mitotic Spindle Organization Spindle Assembly Microtubule Cytoskeleton Organization Involved In Mitosis Centriole Spindle Organization Membraneless Organelle Assembly	RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Positive Regulation Of Termination Of DNA-templated Transcription Glycogen Granule Positive Regulation Of Termination Of RNA Polymerase II Transcription PTW/PP1 Phosphatase Complex RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Androgen Binding Mitochondrial Outer Membrane Meiotic Cytokinesis Formin-nucleated Actin Cable Assembly Parallel Actin Filament Bundle Assembly Establishment Of Meiotic Spindle Localization Polar Body Extrusion After Meiotic Divisions Cleavage Furrow Formation Actin Filament Network Formation Broken Chromosome Clustering
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