TMEM168 and PIGP

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		TMEM168	PIGP
Description		transmembrane protein 168	phosphatidylinositol glycan anchor biosynthesis class P
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Membrane Transport Vesicle Nuclear Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Sodium Channel Regulator Activity	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Regulation Of Ubiquitin-dependent Protein Catabolic Process	GPI Anchor Biosynthetic Process
Pathways			Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: CRKL PIGP SPP1	23 interacting genes: C1GALT1 CLK1 CNST DHRSX FIS1 IER3IP1 ITGAM LHFPL3 NABP2 NINJ2 PCMTD2 PLP1 PLP2 PTPN1 SCAMP5 SMAGP SNRNP70 THSD7B TMEM107 TMEM168 TMEM19 TMEM229B UBIAD1
Entrez ID		64418	51227
HPRD ID		07831	05806
Ensembl ID		ENSG00000146802	ENSG00000185808
Uniprot IDs		Q9H0V1	P57054
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Metabolic Process Helper T Cell Diapedesis Chordate Pharynx Development Cerebellar Neuron Development Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Endothelin Receptor Signaling Pathway Regulation Of Cell Growth Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Neuron Projection Development Extrinsic Component Of Postsynaptic Membrane Diapedesis Positive Regulation Of Glial Cell Migration Positive Regulation Of Receptor Clustering B Cell Apoptotic Process Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Reelin-mediated Signaling Pathway Parathyroid Gland Development Postsynaptic Specialization Assembly Positive Regulation Of Bone Resorption Response To Macrophage Colony-stimulating Factor Androgen Catabolic Process Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Cellular Response To Testosterone Stimulus Negative Regulation Of Neuron Projection Regeneration Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphatidylinositol N-acetylglucosaminyltransferase Activity Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Cellular Response To Interleukin-7 Hormone Catabolic Process Response To Interleukin-7 Urogenital System Development Cranial Skeletal System Development Positive Regulation Of Rac Protein Signal Transduction Response To Peptide Response To Cytokine Regulation Of Receptor Clustering Regulation Of Plasma Membrane Bounded Cell Projection Organization Postsynaptic Specialization Organization Regulation Of Growth Negative Regulation Of SMAD Protein Signal Transduction Retinoic Acid Receptor Signaling Pathway Regulation Of Cell Projection Organization Regulation Of Glial Cell Migration Regulation Of Collateral Sprouting Decidualization Response To Vitamin D Regulation Of Axon Regeneration
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