PGA4 and C16orf92

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PGA4	C16orf92
Description		pepsinogen A4	chromosome 16 open reading frame 92
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Exosome Multivesicular Body Lumen	Plasma Membrane Membrane
	Molecular Function	Aspartic-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity	Protein Binding
	Biological Process	Proteolysis Digestion	Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Fertilization
Pathways		Surfactant metabolism
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 25056061 29483656)
Interacting Genes		9 interacting genes: AMIGO1 C16orf92 CD74 FNDC9 HHLA2 PVR SPAG4 STOM TMEM106C	10 interacting genes: CXCL9 LRP10 MYADM NSG1 PGA4 PLPP6 RETREG3 SEC22A STATH TMEM35A
Entrez ID		643847	146378
HPRD ID		18942
Ensembl ID		ENSG00000229183	ENSG00000167194
Uniprot IDs		A0A1S5UZ02 B7Z719 P0DJD7	Q96LL3
PDB IDs		1FLH 1PSN 1PSO 1QRP 3UTL
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Extracellular Matrix Constituent, Lubricant Activity Endoplasmic Reticulum Spontaneous Synaptic Transmission
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