RBM26 and NDFIP2

		RBM26	NDFIP2
Description		RNA binding motif protein 26	Nedd4 family interacting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Cytoplasm Mitochondrion Endosome Endoplasmic Reticulum Golgi Apparatus Endosome Membrane Membrane Multivesicular Body Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding WW Domain Binding
	Biological Process		Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Negative Regulation Of Gene Expression Metal Ion Transport Positive Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Protein Transport
Pathways		Nuclear RNA decay
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Hip circumference ( 28552196) Metabolite levels ( 23823483) Nickel levels ( 26025379) Response to anti-TNF alpha therapy in inflammatory bowel disease ( 20014019) Systolic blood pressure ( 30224653)	Bullous pemphigoid ( 34011352) Leisure-time exercise behaviour (age-stratified) ( 30102679) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Pancreatic cancer ( 20686608) Smoking status (ever vs never smokers) ( 30643258) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		8 interacting genes: ATXN1 CDKN2A CEBPA CTNNA1 FXR1 HINFP NCK2 SRSF8	9 interacting genes: AQP2 ITCH LYN NEDD4 NEDD4L SMURF1 UQCRH WWP2 YAP1
Entrez ID		64062	54602
HPRD ID		12611	17629
Ensembl ID		ENSG00000139746	ENSG00000102471
Uniprot IDs		A0A087X0H9 Q5T8P6	B4DGY6 Q9NV92
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription Regulation Of Cell Development Positive Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Nucleolus Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Cell Population Proliferation Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription RNA Metabolic Process Negative Regulation Of Cell Development Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Multicellular Organismal Development Regulation Of Protein Metabolic Process RNA Binding Ligase Inhibitor Activity RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Differentiation Cellular Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Positive Regulation Of Signal Transduction Protein-containing Complex Binding Regulation Of Neurogenesis Positive Regulation Of RNA Biosynthetic Process Regulation Of Cell Population Proliferation Positive Regulation Of Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleus Organization Positive Regulation Of Cell Communication Positive Regulation Of Signaling Response To Vitamin B2 C/EBP Complex	Negative Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Receptor Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Ubiquitin-protein Transferase Activity Negative Regulation Of Potassium Ion Transport Protein Polyubiquitination Transmembrane Transporter Binding Ubiquitin Protein Ligase Activity Receptor Metabolic Process Regulation Of Cell Projection Organization C-X-C Chemokine Receptor CXCR4 Signaling Pathway Protein Monoubiquitination Bud Elongation Involved In Lung Branching Regulation Of Nervous System Development Sodium Channel Inhibitor Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Developmental Process Positive Regulation Of Protein Metabolic Process Receptor Internalization Negative Regulation Of Cation Transmembrane Transport Protein K63-linked Ubiquitination Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Synapse Organization Regulation Of Monoatomic Cation Transmembrane Transport Branch Elongation Of An Epithelium Negative Regulation Of Signal Transduction Negative Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Monoatomic Ion Transport Negative Regulation Of Signaling Negative Regulation Of Cell Communication Tolerance Induction Proline-rich Region Binding Protein Ubiquitination Axis Elongation Negative Regulation Of Transmembrane Transport Innervation Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Dendrite Extension Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metal Ion Transport Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Regulation Of Neurogenesis Positive Regulation Of Macromolecule Metabolic Process
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