SEL1L and RPL6

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SEL1L	RPL6
Gene Name		sel-1 suppressor of lin-12-like (C. elegans)	ribosomal protein L6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding	DNA Binding RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding
	Biological Process	Notch Signaling Pathway Response To Endoplasmic Reticulum Stress	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Transcription, DNA-templated Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Hedgehog ligand biogenesis Pre-NOTCH Processing in Golgi Signaling by NOTCH Processing-defective Hh variants abrogate ligand secretion Hh ligand biogenesis disease Signaling by Hedgehog Pre-NOTCH Expression and Processing	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Blood pressure ( 21572416) Esophageal cancer ( 21642993)
Protein-Protein Interactions		1 interactors: RPL6	12 interactors: CSNK2A1 EIF6 FGF2 IL7R IVNS1ABP MAP3K14 ND1 NFKB2 NPAS2 RPL29 SEL1L STAU1
Entrez ID		6400	6128
HPRD ID		07532	04745
Ensembl ID		ENSG00000071537	ENSG00000089009
Uniprot IDs		Q3ZCU6 Q9UBV2	Q02878 Q8TBK5
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Translational Termination Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Protein Targeting To Membrane Translational Elongation RNA Catabolic Process Cellular Protein Complex Disassembly Viral Life Cycle Protein Complex Disassembly Establishment Of Protein Localization To Membrane Translational Initiation	NIK/NF-kappaB Signaling I-kappaB Kinase/NF-kappaB Signaling Rhythmic Process Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Follicular Dendritic Cell Differentiation Interleukin-7-mediated Signaling Pathway Negative Regulation Of Cell Death
Tagcloud ?		asymmetric belonged cleared crystallization crystals diffracted diffraction diffusion dislocation drop e3 erad hanging hrd1 lin machinery misfolded optimized precipitant preliminary propanol ray selecting solvent synchrotron terminally transporting unassembled vapour	60s 80s atpases biogenesis comes ebp2 es39l es7l eukaryote excessively helicases machines mak5 multitude nop1 nop16 nop4 nsa1 nucleolus orchestrate ribosomes rix7 rpf1 rpl14 rpl16 rrnas snornp translate translating
Tagcloud (Difference) ?		asymmetric belonged cleared crystallization crystals diffracted diffraction diffusion dislocation drop e3 erad hanging hrd1 lin machinery misfolded optimized precipitant preliminary propanol ray selecting solvent synchrotron terminally transporting unassembled vapour	60s 80s atpases biogenesis comes ebp2 es39l es7l eukaryote excessively helicases machines mak5 multitude nop1 nop16 nop4 nsa1 nucleolus orchestrate ribosomes rix7 rpf1 rpl14 rpl16 rrnas snornp translate translating
Tagcloud (Intersection) ?