MUC4

Gene Name		mucin 4, cell surface associated
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Golgi Lumen Integral Component Of Plasma Membrane Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	ErbB-2 Class Receptor Binding Extracellular Matrix Constituent, Lubricant Activity
	Biological Process	Protein O-linked Glycosylation Cell-matrix Adhesion O-glycan Processing Maintenance Of Gastrointestinal Epithelium Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Post-translational protein modification Termination of O-glycan biosynthesis O-linked glycosylation of mucins O-linked glycosylation
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: ERBB2 GALNT11
Entrez ID		4585
HPRD ID		11829
Ensembl ID		ENSG00000145113
Uniprot IDs		A0T3F4 E9PDY6 Q99102
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Immature T Cell Proliferation In Thymus Protein O-linked Glycosylation Via Threonine Heart Development Negative Regulation Of T Cell Differentiation In Thymus Notch Signaling Involved In Heart Development Positive Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase I Promoter Cell Projection Morphogenesis Cell Part Morphogenesis Cardiovascular System Development Regulation Of Transcription From RNA Polymerase I Promoter Peptidyl-amino Acid Modification Regulation Of Transcription From RNA Polymerase III Promoter Notch Receptor Processing Phosphatidylinositol 3-kinase Signaling Cell Morphogenesis Cell Projection Organization Regulation Of T Cell Differentiation In Thymus Motor Neuron Axon Guidance Negative Regulation Of T Cell Differentiation Negative Regulation Of Lymphocyte Differentiation O-glycan Processing Neuromuscular Junction Development Negative Regulation Of T Cell Proliferation Regulation Of Notch Signaling Pathway Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Positive Regulation Of Translation Oligodendrocyte Differentiation Protein O-linked Glycosylation Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion
Tagcloud ?		bc circumvent critically dm1 dramatic efforts emerging expanding exploit family her2 holds immunity improvements overexpress p27kip1 p95her2 pan pi3k positivity pten repertoire rtk rtks signalling targeted therapies trastuzumab worse