MANBAL and MPDU1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MANBAL	MPDU1
Description		mannosidase beta like	mannose-P-dolichol utilization defect 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Protein Folding Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide Biosynthetic Process
Pathways			Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective MPDU1 causes CDG-1f
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Appendicular lean mass ( 33097823)	Brain morphology (MOSTest) ( 32665545) Hemoglobin levels ( 32327693) IgA nephropathy ( 22197929) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: ATP13A1 CACNA1A CATSPERH CMTM2 GPR151 KLK5 MALL MARCHF5 MPDU1 NIPAL3 OTOP2 PIGF SCRG1 SLC39A9 STX3 TMBIM6 TMEM115 TMEM203 UBQLN1 VKORC1 VTI1B	3 interacting genes: LSM1 MANBAL SHBG
Entrez ID		63905	9526
HPRD ID		14356	04951
Ensembl ID		ENSG00000101363	ENSG00000129255
Uniprot IDs		A2A2E0 Q9NQG1	A0A0S2Z4W8 B4DLH7 J3QW43 O75352
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Monoatomic Ion Transport Metal Ion Transport Endoplasmic Reticulum SNARE Complex Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane SNAP Receptor Activity Intracellular Calcium Ion Homeostasis Endoribonuclease Inhibitor Activity Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Negative Regulation Of Calcium Ion Transport Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Transmembrane Transport Intracellular Monoatomic Cation Homeostasis Inorganic Ion Homeostasis Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Autophagosome Maturation Presynaptic Endosome Membrane Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Regulation Of Cellular Response To Testosterone Stimulus Zinc Efflux Transmembrane Transporter Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Vesicle Docking Monoatomic Ion Homeostasis SNARE Binding Negative Regulation Of Cation Transmembrane Transport Chemical Homeostasis Ethanolaminephosphotransferase Activity Intracellular Chemical Homeostasis Negative Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Toll-like Receptor 3 Signaling Pathway P-type Transmembrane Transporter Activity	Androgen Binding Lsm1-7-Pat1 Complex Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Decapping MRNA Methylguanosine-cap Decapping Histone MRNA Catabolic Process Histone MRNA Metabolic Process Steroid Binding
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