SCML1 and RENBP

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		SCML1	RENBP
Name		Scm polycomb group protein like 1	renin binding protein
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Endopeptidase Inhibitor Activity Protein Binding Isomerase Activity Peptidase Inhibitor Activity Identical Protein Binding N-acylglucosamine 2-epimerase Activity
	Biological Process	Negative Regulation Of DNA-templated Transcription	Carbohydrate Metabolic Process Amino Sugar Metabolic Process N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process Regulation Of Blood Pressure N-acetylneuraminate Catabolic Process
Pathways		None	Synthesis of UDP-N-acetyl-glucosamine
Drugs		None	N-Acetylglucosamine
GWAS		Metabolite levels ( 23823483 )	Schizophrenia ( 24043878 ) Systemic lupus erythematosus ( 26502338 )
Interacting Genes		5 interacting genes: ITGB2 LNX1 RENBP SDCBP SFMBT2	3 interacting genes: REN SCML1 ZBED1
Entrez ID		6322	5973
HPRD ID		02205	02423
Ensembl ID		ENSG00000047634	ENSG00000102032
Uniprot IDs		Q9UN30	P51606
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Integrin AlphaM-beta2 Complex Integrin AlphaX-beta2 Complex Extracellular Vesicle Positive Regulation Of Exocytosis Integrin AlphaL-beta2 Complex N-acylglucosamine 2-epimerase Activity N-acetylmannosamine Metabolic Process Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex Regulation Of Exocytosis ICAM-3 Receptor Activity Negative Regulation Of Dopamine Metabolic Process Positive Regulation Of Neutrophil Degranulation Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Membrane Raft Negative Regulation Of Catecholamine Metabolic Process N-acetylneuraminate Catabolic Process Regulation Of Extracellular Exosome Assembly Regulation Of Neutrophil Degranulation Positive Regulation Of Secretion By Cell Substrate-dependent Cell Migration, Cell Extension	Juxtaglomerular Apparatus Development Mesonephros Development Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Angiotensin Maturation Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Regulation Of Blood Volume By Renin-angiotensin Drinking Behavior Renin-angiotensin Regulation Of Aldosterone Production Response To CGMP SUMO Ligase Activity Protein Autosumoylation Host-mediated Suppression Of Viral Genome Replication Angiotensin-activated Signaling Pathway Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Aspartic-type Endopeptidase Activity Insulin-like Growth Factor Receptor Binding SUMO Transferase Activity Response To Immobilization Stress Amyloid-beta Metabolic Process Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Peptide Hormone Processing Regulation Of Systemic Arterial Blood Pressure Signaling Receptor Ligand Precursor Processing