S100A7 and PITRM1

		S100A7	PITRM1
Description		S100 calcium binding protein A7	pitrilysin metallopeptidase 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Extracellular Matrix Azurophil Granule Lumen	Mitochondrion Mitochondrial Matrix
	Molecular Function	Calcium Ion Binding Protein Binding Zinc Ion Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding Zinc Ion Sequestering Activity	Metalloendopeptidase Activity Protein Binding Enzyme Activator Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Epidermis Development Positive Regulation Of T Cell Chemotaxis Keratinocyte Differentiation Response To Lipopolysaccharide Endothelial Cell Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis	Proteolysis Protein Targeting To Mitochondrion Protein Processing
Pathways		Neutrophil degranulation Metal sequestration by antimicrobial proteins	Mitochondrial protein import
Drugs		Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576)	Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)
Interacting Genes		9 interacting genes: CLVS2 COPS5 EGFR FABP5 RANBP9 S100A7L2 TGM2 UCHL5 WEE2-AS1
Entrez ID		6278	10531
HPRD ID		02645	07142
Ensembl ID		ENSG00000143556	ENSG00000107959
Uniprot IDs		P31151	A0A0A0MRX9 A0A7I2V397 Q5JRX3
PDB IDs		1PSR 2PSR 2WND 2WOR 2WOS 3PSR 4AQJ	4L3T 4NGE 4RPU 6XOS 6XOT 6XOU 6XOV 6XOW
Enriched GO Terms of Interacting Partners?		Multivesicular Body, Internal Vesicle Lumen Peptide Dopaminyltransferase Activity Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptidase Activity Peptide Serotonyltransferase Activity Histone Dopaminyltransferase Activity Lysosome Organization	Protein Targeting To Mitochondrion
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