RPL21 and HNRNPA1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		RPL21	HNRNPA1
Gene Name		ribosomal protein L21	heterogeneous nuclear ribonucleoprotein A1
Image
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit	Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Ribonucleoprotein Complex Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding	Nucleotide Binding Single-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus RNA Splicing Gene Expression Viral Process MRNA Transport Nuclear Export Nuclear Import
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Electrocardiographic traits ( 17903306)
Protein-Protein Interactions		3 interactors: HNRNPA1 PIM2 VHL	32 interactors: ABHD16A APP ERG FEN1 HIPK3 HIST3H3 HMGA1 HNRNPH3 KHSRP NFKBIA NR0B2 NR3C1 PABPN1 PHYHIP PPIL1 PRKDC PRMT1 PRMT2 PRMT3 PRRC2A RNF14 RPL21 SAFB SREK1 SRPK1 SUFU TFEC TNPO1 TRA2B TTF2 XRN1 YWHAQ
Entrez ID		6144	3178
HPRD ID		04700	01242
Ensembl ID		ENSG00000122026	ENSG00000135486
Uniprot IDs		P46778 Q6IAX2	P09651
PDB IDs		3J3B	1HA1 1L3K 1PGZ 1PO6 1U1K 1U1L 1U1M 1U1N 1U1O 1U1P 1U1Q 1U1R 1UP1 2H4M 2LYV 2UP1
Enriched GO Terms of Interacting Partners?		Protein Stabilization Regulation Of Protein Stability Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Posttranscriptional Regulation Of Gene Expression	MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Processing Regulation Of Gene Expression Nitrogen Compound Metabolic Process RNA Splicing Regulation Of Nitrogen Compound Metabolic Process RNA Processing Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromosome Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Peptidyl-arginine N-methylation Positive Regulation Of Gene Expression Histone Arginine Methylation Peptidyl-arginine Methylation Intracellular Receptor Signaling Pathway Cellular Metabolic Process RNA Splicing, Via Transesterification Reactions RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Metabolic Process Chromatin Organization Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Catabolic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Telomere Maintenance Peptidyl-amino Acid Modification Cellular Macromolecule Biosynthetic Process Regulation Of MRNA Processing MRNA Splicing, Via Spliceosome Aromatic Compound Catabolic Process Macromolecule Biosynthetic Process Regulation Of Androgen Receptor Signaling Pathway Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?			amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution taf15 tardbp tdp43 tremor
Tagcloud (Difference) ?			amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution taf15 tardbp tdp43 tremor
Tagcloud (Intersection) ?