KRTAP5-8 and LCE1E

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRTAP5-8	LCE1E
Description		keratin associated protein 5-8	late cornified envelope 1E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Identical Protein Binding
	Biological Process		Epidermis Development Keratinization
Pathways		Keratinization	Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma ( 31619474) Inflammatory skin disease ( 25574825)
Interacting Genes		6 interacting genes: CRCT1 HHEX LCE1E LCE3A LCE5A WNT11	67 interacting genes: ALPP CATSPER1 CYSRT1 EFEMP2 FAM9A FUCA2 GRN KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2B LCE2C LCE2D LCE3B LCE4A LCE5A MACO1 MEOX2 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 PIAS2 RGS17 RGS20 RNF4 SMCP SPRY1 TGM1 TRIM42 ZCCHC7
Entrez ID		57830	353135
HPRD ID		17252	13969
Ensembl ID		ENSG00000241233	ENSG00000186226
Uniprot IDs		O75690	Q5T753
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Tissue Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Transcription By Competitive Promoter Binding Regulation Of MRNA Export From Nucleus Negative Regulation Of Cytoplasmic Translational Initiation Eukaryotic Initiation Factor 4E Binding Regionalization Secondary Palate Development Notochord Morphogenesis Nephron Tubule Morphogenesis Convergent Extension Involved In Axis Elongation Lung-associated Mesenchyme Development Negative Regulation Of Fibroblast Growth Factor Production Maintenance Of Epithelial Cell Apical/basal Polarity Primary Heart Field Specification Ureteric Bud Morphogenesis Wnt Signaling Pathway, Calcium Modulating Pathway Convergent Extension Cloacal Septation Positive Regulation Of Transforming Growth Factor Beta2 Production Atrial Septum Development Nephric Duct Development Regulation Of Transforming Growth Factor Beta2 Production Heart Field Specification Mesonephric Duct Development Negative Regulation Of Mesenchymal Cell Proliferation Paraxial Mesoderm Formation Secondary Heart Field Specification Maintenance Of Cell Polarity Regulation Of Wnt Signaling Pathway DNA Binding, Bending Somite Development Regulation Of RNA Export From Nucleus Translation Regulator Activity DNA Conformation Change Specification Of Animal Organ Identity Renal Tubule Morphogenesis Neuroendocrine Cell Differentiation Positive Regulation Of Transforming Growth Factor Beta Production Pattern Specification Process Positive Regulation Of Epithelial Cell Apoptotic Process Adrenal Gland Development TBP-class Protein Binding Mesenchymal Cell Proliferation	Intermediate Filament Keratin Filament Keratinization Epidermis Development Hair Cycle Tissue Development Cytosol Protein Binding Identical Protein Binding
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