UVSSA and MAGEA4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UVSSA	MAGEA4
Description		UV stimulated scaffold protein A	MAGE family member A4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Site Of DNA Damage	Nucleus
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Zinc Ion Binding Metal Ion Binding Chromatin-protein Adaptor Activity RNA Polymerase Inhibitor Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	DNA Repair Transcription-coupled Nucleotide-excision Repair Chromatin Organization DNA Damage Response Response To UV Protein Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Cycle
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Chronotype ( 30696823)
Interacting Genes		8 interacting genes: ERCC8 KPNA3 MAGEA4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1	27 interacting genes: AMOT AMOTL2 APP ARNT2 BEX2 COX8A GTF3C1 HDDC3 HLA-A LDLRAP1 PICK1 POT1 PSMD10 PUDP RAD18 TEKT4 TIGD5 TK1 TRIM69 TSPYL1 TSPYL4 TXN2 UBXN6 UQCRB UVSSA WBP2 ZNF576
Entrez ID		57654	4103
HPRD ID		17216	02167
Ensembl ID		ENSG00000163945	ENSG00000147381
Uniprot IDs		A0A7I2V4K1 Q2YD98	P43358
PDB IDs		5XV8 7OO3 7OOP 7OPC 7OPD 8B3D 8B3G 8QH5 9BZ0 9ER2 9FD2	1I4F 2WA0 6TRN 6TRO 7UOA 8ES8 8ES9 8FJA 9BD3
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein K48-linked Ubiquitination Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification Macromolecule Catabolic Process Proteolysis Protein Autoubiquitination Protein Modification Process Catabolic Process Protein K6-linked Ubiquitination Protein K11-linked Ubiquitination ATP Binding Protein Monoubiquitination Nucleus Regulation Of Transcription-coupled Nucleotide-excision Repair Nucleotide Binding Negative Regulation Of BMP Signaling Pathway Ubiquitin Protein Ligase Activity Transferase Activity Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of BMP Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Viral Penetration Into Host Nucleus ISG15 Transferase Activity Protein Catabolic Process Nucleoplasm Nucleotide-excision Repair Complex Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway ISG15-protein Conjugation Intracellular Transport Of Virus Protein-containing Complex Host Cell NLS-dependent Protein Nuclear Import Complex Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair Transcription-coupled Nucleotide-excision Repair Protein K29-linked Ubiquitination Cul4A-RING E3 Ubiquitin Ligase Complex Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Protein K27-linked Ubiquitination	Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
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