MIR363 and DARS1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR363	DARS1
Description		microRNA 363	aspartyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Synapse Extracellular Exosome
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleotide Binding Nucleic Acid Binding RNA Binding Aminoacylase Activity Aminoacyl-tRNA Ligase Activity Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	Translation TRNA Aminoacylation For Protein Translation Aspartyl-tRNA Aminoacylation Protein-containing Complex Assembly
Pathways			Selenoamino acid metabolism Cytosolic tRNA aminoacylation Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs			Aspartic acid
Diseases
GWAS
Interacting Genes		94 interacting genes: ADARB1 APOBEC3B ATXN2L C1QBP CDC5L CELF1 CELF2 CHERP DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KIN LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PURA PURB QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCA RTCB SAFB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	80 interacting genes: AIMP2 CEBPA DSCR9 EEF1A1 ERCC6 ESR1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PIK3R3 SUMO2
Entrez ID		574031	1615
HPRD ID			04361
Ensembl ID		ENSG00000284499	ENSG00000115866
Uniprot IDs			A0A140VJW5 P14868
PDB IDs			4J15 5Y6L 6IY6
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Metabolic Process Nucleic Acid Metabolic Process MRNA Processing RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Splicing Macromolecule Metabolic Process Nucleoplasm Nucleus Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression Spliceosomal Complex Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process MiRNA Binding RNA Stabilization TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Negative Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation Regulation Of MRNA Stability Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Locomotion Regulation Of Angiogenesis Positive Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Translation Regulation Of MRNA Stability Negative Regulation Of Multicellular Organismal Process Regulation Of RNA Stability Negative Regulation Of Developmental Process Extracellular Space Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Migration Regulation Of Cell Motility Negative Regulation Of Signal Transduction Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Blood Vessel Endothelial Cell Migration
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