RGL3 and FAM200A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RGL3	FAM200A
Description		ral guanine nucleotide dissociation stimulator like 3	family with sequence similarity 200 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Signal Transduction Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction
Pathways		RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure ( 27618447 27618448 27841878) Hypertension ( 27618447 27618448 32709000 31879980) Mean arterial pressure ( 27618448) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Pulse pressure ( 27841878 27618447) Systolic blood pressure ( 28135244 27841878 30578418 27618448 27618447)
Interacting Genes		6 interacting genes: FAM200A KLHL12 NRAS RIT1 RIT2 RRAS2	4 interacting genes: APP RBM39 RGL3 SUMO1P1
Entrez ID		57139	221786
HPRD ID		18844	13221
Ensembl ID		ENSG00000205517	ENSG00000221909
Uniprot IDs		Q3MIN7	Q8TCP9
PDB IDs
Enriched GO Terms of Interacting Partners?		Ras Protein Signal Transduction GDP Binding Small GTPase-mediated Signal Transduction G Protein Activity GTPase Activity GTP Binding Intracellular Signaling Cassette Hydrolase Activity Dendritic Tree Positive Regulation Of Schwann Cell Migration Schwann Cell Migration Nucleotide Binding Intracellular Signal Transduction Calmodulin Binding MAPK Cascade Neural Crest Formation Positive Regulation Of Glial Cell Migration Regulation Of Cdc42 Protein Signal Transduction Signal Transduction	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway RS Domain Binding Axon Choice Point Recognition U1 SnRNP Binding PML Body Organization Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle
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