NAT14 and ISOC2

		NAT14	ISOC2
Description		N-acetyltransferase 14 (putative)	isochorismatase domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Membrane	Nucleus Cytoplasm Mitochondrion
	Molecular Function	DNA Binding Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups	Protein Binding
	Biological Process	DNA-templated Transcription Initiation Positive Regulation Of DNA-templated Transcription	Protein Destabilization
Pathways
Drugs
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: ADRB2 CCR4 F2RL1 HTR2B JUN RABAC1 YAE1	5 interacting genes: APP CALML3 CDKN2A LSM8 PDK2
Entrez ID		57106	79763
HPRD ID		10036	08030
Ensembl ID		ENSG00000090971	ENSG00000063241
Uniprot IDs		Q8WUY8	Q96AB3
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of ERK1 And ERK2 Cascade Regulation Of MAPK Cascade Modulation Of Process Of Another Organism Blood Vessel Diameter Maintenance G Protein-coupled Receptor Activity Regulation Of Tube Size G-protein Alpha-subunit Binding Positive Regulation Of Protein-containing Complex Disassembly Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Mini Excitatory Postsynaptic Potential Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Vasodilation Smooth Muscle Contraction Positive Regulation Of Intracellular Signal Transduction Vascular Process In Circulatory System Beta2-adrenergic Receptor Activity Proteinase-activated Receptor Activity Positive Regulation Of Eosinophil Degranulation Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Leading Edge Cell Differentiation Behavioral Response To Starvation Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Early Endosome Amyloid-beta Binding Beta-adrenergic Receptor Activity Circulatory System Process Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process Cellular Response To Anisomycin Positive Regulation Of Endothelial Cell Proliferation	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Signal Transduction Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Calcium-mediated Signaling Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Amyloid Fibril Formation Regulation Of Calcium-mediated Signaling Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Response To Reactive Oxygen Species Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Senescence-associated Heterochromatin Focus Ligase Inhibitor Activity Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Cellular Response To Reactive Oxygen Species Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway
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