SHD and TRIP4

Number of citations of the paper that reports this interaction (PMID 10454579)
8

Data Source:
BioGRID (pull down)

		SHD	TRIP4
Gene Name		Src homology 2 domain containing transforming protein D	thyroid hormone receptor interactor 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center
	Molecular Function	Protein Binding	Protease Binding Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ligand-dependent Nuclear Receptor Binding Estrogen Receptor Binding Histone Acetyltransferase Binding Ubiquitin-like Protein Ligase Binding
	Biological Process		Transcription From RNA Polymerase II Promoter Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Toxin Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ABL1 TRIP4	22 interactors: AR ASCC2 ASCC3 CREBBP EP300 ESR1 ESR2 GTF2A1 JUN NCOA1 NEK6 NFKB1 NR2F2 PAX9 PPARG RARA RELA RXRA SHD TBP THRB XBP1
Entrez ID		56961	9325
HPRD ID		15337	05140
Ensembl ID		ENSG00000105251	ENSG00000103671
Uniprot IDs		Q96IW2	Q15650
PDB IDs			2E5O
Enriched GO Terms of Interacting Partners?		Transitional One Stage B Cell Differentiation Negative Regulation Of Phospholipase C Activity Mitochondrial Depolarization Cellular Response To Dopamine Actin Filament Branching Positive Regulation Of Interferon-gamma Secretion Collateral Sprouting Microspike Assembly B Cell Proliferation Involved In Immune Response Bergmann Glial Cell Differentiation Negative Regulation Of Phospholipase Activity B-1 B Cell Homeostasis Negative Regulation Of Cellular Senescence Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Interleukin-2 Secretion Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Non-canonical Wnt Signaling Pathway DNA Damage Induced Protein Phosphorylation Negative Regulation Of Cell Aging Immature B Cell Differentiation Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Lipase Activity Cellular Response To Ammonium Ion Regulation Of Osteoblast Proliferation Negative Regulation Of Endothelial Cell Apoptotic Process Regulation Of Cellular Senescence Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cellular Response To Catecholamine Stimulus Activated T Cell Proliferation Regulation Of Mitochondrial Membrane Potential Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Interleukin-2 Production B Cell Homeostasis Positive Regulation Of Calcium Ion Transport Into Cytosol Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Oxidoreductase Activity Regulation Of Actin Cytoskeleton Reorganization Regulation Of Extracellular Matrix Organization B Cell Receptor Signaling Pathway Toxin Transport Astrocyte Differentiation B Cell Proliferation Negative Regulation Of BMP Signaling Pathway Spleen Development Substrate Adhesion-dependent Cell Spreading B Cell Activation Involved In Immune Response Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cerebellum Morphogenesis	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Intracellular Receptor Signaling Pathway Response To Lipid Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression DNA-templated Transcription, Initiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Steroid Hormone Mediated Signaling Pathway Cellular Response To Hormone Stimulus Cellular Response To Lipid Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Steroid Hormone Regulation Of RNA Metabolic Process Response To Hormone Hormone-mediated Signaling Pathway Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Cyclic Compound Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Cellular Response To Steroid Hormone Stimulus Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Gland Development
Tagcloud ?		advice call calling calls closer confirmation convenience convenient deeper expert father gastroenteritis get guidance inductively inhabitants interviewed let nurse opportunity parents security seeker seemed sick subcategories swedish telephone vulnerable	abca7 bin1 cass4 cd2ap cd33 celf1 chapter discoveries drb1 drb5 epha1 fermt2 inpp5d mef2c ms4a4 ms4a6 nme8 picalm pld3 psen1 psen2 ptk2b rin3 slc24a4 sorl1 touch trem2 unsuspected zcwpw1
Tagcloud (Difference) ?		advice call calling calls closer confirmation convenience convenient deeper expert father gastroenteritis get guidance inductively inhabitants interviewed let nurse opportunity parents security seeker seemed sick subcategories swedish telephone vulnerable	abca7 bin1 cass4 cd2ap cd33 celf1 chapter discoveries drb1 drb5 epha1 fermt2 inpp5d mef2c ms4a4 ms4a6 nme8 picalm pld3 psen1 psen2 ptk2b rin3 slc24a4 sorl1 touch trem2 unsuspected zcwpw1
Tagcloud (Intersection) ?